Pr MEYRE David

Methionine Synthase Interacts With the Methionine Adenosyl-Transferase MATα2 and the DNA Methyltransferase DNMT3b in the Nucleus.

Jeandel M, Alberto JM, Baspinar O, Robert A, Dreumont N, Alsahly Z, Meyre D, Guéant JL, Coelho D

J Inherit Metab Dis. 2026 07;49(4):e70211

Replication Study of ENPP1 Variants and Haplotypes Associated with Severe Obesity in a Greek Adult Population.

Rouskas K, Meyre D, Lobbens S, Papazoglou D, Kouvatsi A, Froguel P

Biochem Genet. 2026 06 20;:

Natural selection signatures of 65 syndromic and 8 monogenic obesity genes in 7 ethnic groups do not support the thrifty genotype hypothesis.

El Kouche S, Meyre D

Metabolism. 2025 07 23;:156353

adverSCarial: assessing the vulnerability of single-cell RNA-sequencing classifiers to adversarial attacks.

Fievet G, Broséus J, Meyre D, Hergalant S

Bioinformatics. 2025 04 15;:

Early stage of metabolic dysfunction associated steatotic liver disease disrupts circadian rhythm and induces neuroinflammation in rats.

Graindorge PH, Paoli J, Yildirim B, Morel C, Herzine A, Collin M, Gallais I, Boucard S, Pouyatos B, Meyre D, Lagadic-Gossmann D, Sergent O, Schroeder H, Grova N

Sci Rep. 2025 03 27;15(1):10616

Pollution, stress response, and obesity: A systematic review.

El Kouche S, Halvick S, Morel C, Duca RC, van Nieuwenhuyse A, Turner JD, Grova N, Meyre D

Obes Rev. 2025 01 17;:e13895

Body mass index trajectories and their predictors in undergraduate students from Canada: Results from the GENEiUS study.

Sharma T, Morassut RE, Langlois C, Meyre D

J Am Coll Health. 2024 10;72(7):2147-2155

Medical semiology of patients with monogenic obesity: A systematic review.

Renard E, Thevenard-Berger A, Meyre D

Obes Rev. 2024 10;25(10):e13797

Sequencing methods, functional characterization, prevalence, and penetrance of rare coding mutations in panels of monogenic obesity genes from the leptin-melanocortin pathway: A systematic review.

Dosda S, Renard E, Meyre D

Obes Rev. 2024 08;25(8):e13754

Molecular characterization of Richter syndrome identifies de novo diffuse large B-cell lymphomas with poor prognosis.

Broséus J, Hergalant S, Vogt J, Tausch E, Kreuz M, Mottok A, Schneider C, Dartigeas C, Roos-Weil D, Quinquenel A, Moulin C, Ott G, Blanchet O, Tomowiak C, Lazarian G, Rouyer P, Chteinberg E, Bernhart SH, Tournilhac O, Gauchotte G, Lomazzi S, Chapiro E, Nguyen-Khac F, Chery C, Davi F, Hunault M, Houlgatte R, Rosenwald A, Delmer A, Meyre D, Béné MC, Thieblemont C, Lichter P, Ammerpohl O, Guéant JL, ,Guièze R, Martin-Subero JI, Cymbalista F, Feugier P, Siebert R, Stilgenbauer S

Nat Commun. 2023 01 19;14(1):309

Association of total and pancreatic serum amylase enzymatic activity with insulin resistance and the glucose and insulin responses to oral starch test in Mexican children.

Locia-Morales D, Vázquez-Moreno M, González-Dzib R, Domínguez-Hernández C, Pérez-Herrera A, Robles-Ramírez RJ, Rocha-Cruz A, Meyre D, Flores-Alfaro E, Cruz M

Pediatr Obes. 2022 12;17(12):e12965

Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention.

Wang Z, Emmerich A, Pillon NJ, Moore T, Hemerich D, Cornelis MC, Mazzaferro E, Broos S, Ahluwalia TS, Bartz TM, Bentley AR, Bielak LF, Chong M, Chu AY, Berry D, Dorajoo R, Dueker ND, Kasbohm E, Feenstra B, Feitosa MF, Gieger C, Graff M, Hall LM, Haller T, Hartwig FP, Hillis DA, Huikari V, Heard-Costa N, Holzapfel C, Jackson AU, Johansson Å, Jørgensen AM, Kaakinen MA, Karlsson R, Kerr KF, Kim B, Koolhaas CM, Kutalik Z, Lagou V, Lind PA, Lorentzon M, Lyytikäinen LP, Mangino M, Metzendorf C, Monroe KR, Pacolet A, Pérusse L, Pool R, Richmond RC, Rivera NV, Robiou-du-Pont S, Schraut KE, Schulz CA, Stringham HM, Tanaka T, Teumer A, Turman C, van der Most PJ, Vanmunster M, van Rooij FJA, van Vliet-Ostaptchouk JV, Zhang X, Zhao JH, Zhao W, Balkhiyarova Z, Balslev-Harder MN, Baumeister SE, Beilby J, Blangero J, Boomsma DI, Brage S, Braund PS, Brody JA, Bruinenberg M, Ekelund U, Liu CT, Cole JW, Collins FS, Cupples LA, Esko T, Enroth S, Faul JD, Fernandez-Rhodes L, Fohner AE, Franco OH, Galesloot TE, Gordon SD, Grarup N, Hartman CA, Heiss G, Hui J, Illig T, Jago R, James A, Joshi PK, Jung T, Kähönen M, Kilpeläinen TO, Koh WP, Kolcic I, Kraft PP, Kuusisto J, Launer LJ, Li A, Linneberg A, Luan J, Vidal PM, Medland SE, Milaneschi Y, Moscati A, Musk B, Nelson CP, Nolte IM, Pedersen NL, Peters A, Peyser PA, Power C, Raitakari OT, Reedik M, Reiner AP, Ridker PM, Rudan I, Ryan K, Sarzynski MA, Scott LJ, Scott RA, Sidney S, Siggeirsdottir K, Smith AV, Smith JA, Sonestedt E, Strøm M, Tai ES, Teo KK, Thorand B, Tönjes A, Tremblay A, Uitterlinden AG, Vangipurapu J, van Schoor N, Völker U, Willemsen G, Williams K, Wong Q, Xu H, Young KL, Yuan JM, Zillikens MC, Zonderman AB, Ameur A, Bandinelli S, Bis JC, Boehnke M, Bouchard C, Chasman DI, Smith GD, de Geus EJC, Deldicque L, Dörr M, Evans MK, Ferrucci L, Fornage M, Fox C, Garland T, Gudnason V, Gyllensten U, Hansen T, Hayward C, Horta BL, Hyppönen E, Jarvelin MR, Johnson WC, Kardia SLR, Kiemeney LA, Laakso M, Langenberg C, Lehtimäki T, Marchand LL, ,Magnusson PKE, Martin NG, Melbye M, Metspalu A, Meyre D, North KE, Ohlsson C, Oldehinkel AJ, Orho-Melander M, Pare G, Park T, Pedersen O, Penninx BWJH, Pers TH, Polasek O, Prokopenko I, Rotimi CN, Samani NJ, Sim X, Snieder H, Sørensen TIA, Spector TD, Timpson NJ, van Dam RM, van der Velde N, van Duijn CM, Vollenweider P, Völzke H, Voortman T, Waeber G, Wareham NJ, Weir DR, Wichmann HE, Wilson JF, Hevener AL, Krook A, Zierath JR, Thomis MAI, Loos RJF, Hoed MD

Nat Genet. 2022 09;54(9):1332-1344

Effects of supplementation on blood concentration and mRNA expression of TNF-, PPAR- and adiponectin, as major adipogenesis-related markers, in obese and overweight women: a crossover, randomised-controlled trial.

Razmpoosh E, Safi S, Nadjarzadeh A, Salehi-Abargouei A, Mazaheri M, Mirmiran P, Meyre D

Br J Nutr. 2022 05 11;:1-10

The effect of vitamin D supplementation on serum levels of fibroblast growth factor- 23: A systematic review and meta-analysis of randomized controlled trials.

Meshkini F, Soltani S, Clark CCT, Tam V, Meyre D, Toupchian O, Saraf-Bank S, Abdollahi S

J Steroid Biochem Mol Biol. 2022 01;215:106012

Low-frequency coding variants associated with body-mass-index impact the success of bariatric surgery.

Antoine D, Guéant-Rodriguez RM, Chèvre JC, Hergalant S, Sharma T, Li Z, Rouyer P, Chery C, Halvick S, Bui C, Oussalah A, Ziegler O, Quilliot D, Brunaud L, Guéant JL, Meyre D

J Clin Endocrinol Metab. 2021 Oct 26;:

Genetic syndromes with diabetes: A systematic review.

Shi D, Motamed M, Mejía-Benítez A, Li L, Lin E, Budhram D, Kaur Y, Meyre D

Obes Rev. 2021 09;22(9):e13303

Consequences of Paternal Nutrition on Offspring Health and Disease.

Dimofski P, Meyre D, Dreumont N, Leininger-Muller B

Nutrients. 2021 08 17;13(8):

Association of gut microbiome with fasting triglycerides, fasting insulin and obesity status in Mexican children.

Vazquez-Moreno M, Perez-Herrera A, Locia-Morales D, Dizzel S, Meyre D, Stearns JC, Cruz M

Pediatr Obes. 2021 05;16(5):e12748

AGT rs4762 is associated with diastolic blood pressure in Mexicans with diabetic nephropathy.

Vázquez-Moreno M, Locia-Morales D, Peralta-Romero J, Sharma T, Meyre D, Cruz M, Flores-Alfaro E, Valladares-Salgado A

J Diabetes Complications. 2021 03;35(3):107826

Effect of sex/gender on obesity traits in Canadian first year university students: The GENEiUS study.

Sharma T, Morassut RE, Langlois C, Meyre D

PLoS One. 2021 02 16;16(2):e0247113

The MC4R p.Ile269Asn mutation confers a high risk for type 2 diabetes in the Mexican population via obesity dependent and independent effects.

Vázquez-Moreno M, Locia-Morales D, Valladares-Salgado A, Sharma T, Perez-Herrera A, Gonzalez-Dzib R, Rodríguez-Ruíz F, Wacher-Rodarte N, Cruz M, Meyre D

Sci Rep. 2021 02 4;11(1):3097

Sex/Gender Modifies the Association Between the MC4R p.Ile269Asn Mutation and Type 2 Diabetes in the Mexican Population.

Vázquez-Moreno M, Locia-Morales D, Valladares-Salgado A, Sharma T, Wacher-Rodarte N, Cruz M, Meyre D

J Clin Endocrinol Metab. 2021 01 1;106(1):e112-e117

The effect of race/ethnicity on obesity traits in first year university students from Canada: The GENEiUS study.

Sharma T, Manoharan B, Langlois C, Morassut RE, Meyre D

PLoS One. 2020 11 25;15(11):e0242714

Effect of living arrangement on anthropometric traits in first-year university students from Canada: The GENEiUS study.

Sharma T, Langlois C, Morassut RE, Meyre D

PLoS One. 2020 11 6;15(11):e0241744

Signatures of natural selection and ethnic-specific prevalence of NPC1 pathogenic mutations contributing to obesity and Niemann-Pick disease type C1.

Chiorean A, Garver WS, Meyre D

Sci Rep. 2020 11 2;10(1):18787

Circulating levels of CTRP3 in patients with type 2 diabetes mellitus compared to controls: A systematic review and meta-analysis.

Moradi N, Najafi M, Sharma T, Fallah S, Koushki M, Peterson JM, Meyre D, Fadaei R

Diabetes Res Clin Pract. 2020 11;169:108453

Obesity status modifies the association between rs7556897T>C in the intergenic region SLC19A3-CCL20 and blood pressure in French children.

El Shamieh S, Stathopoulou MG, Bonnefond A, Ndiaye NC, Lecoeur C, Meyre D, Dadé S, Chedid P, Salami A, Shahabi P, Dedoussis GV, Froguel P, Visvikis-Siest S

Clin Chem Lab Med. 2020 10 25;58(11):1819-1827

Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits.

Vogelezang S, Bradfield JP, Ahluwalia TS, Curtin JA, Lakka TA, Grarup N, Scholz M, van der Most PJ, Monnereau C, Stergiakouli E, Heiskala A, Horikoshi M, Fedko IO, Vilor-Tejedor N, Cousminer DL, Standl M, Wang CA, Viikari J, Geller F, Íñiguez C, Pitkänen N, Chesi A, Bacelis J, Yengo L, Torrent M, Ntalla I, Helgeland Ø, Selzam S, Vonk JM, Zafarmand MH, Heude B, Farooqi IS, Alyass A, Beaumont RN, Have CT, Rzehak P, Bilbao JR, Schnurr TM, Barroso I, Bønnelykke K, Beilin LJ, Carstensen L, Charles MA, Chawes B, Clément K, Closa-Monasterolo R, Custovic A, Eriksson JG, Escribano J, Groen-Blokhuis M, Grote V, Gruszfeld D, Hakonarson H, Hansen T, Hattersley AT, Hollensted M, Hottenga JJ, Hyppönen E, Johansson S, Joro R, Kähönen M, Karhunen V, Kiess W, Knight BA, Koletzko B, Kühnapfel A, Landgraf K, Langhendries JP, Lehtimäki T, Leinonen JT, Li A, Lindi V, Lowry E, Bustamante M, Medina-Gomez C, Melbye M, Michaelsen KF, Morgen CS, Mori TA, Nielsen TRH, Niinikoski H, Oldehinkel AJ, Pahkala K, Panoutsopoulou K, Pedersen O, Pennell CE, Power C, Reijneveld SA, Rivadeneira F, Simpson A, Sly PD, Stokholm J, Teo KK, Thiering E, Timpson NJ, Uitterlinden AG, van Beijsterveldt CEM, van Schaik BDC, Vaudel M, Verduci E, Vinding RK, Vogel M, Zeggini E, Sebert S, Lind MV, Brown CD, Santa-Marina L, Reischl E, Frithioff-Bøjsøe C, Meyre D, Wheeler E, Ong K, Nohr EA, Vrijkotte TGM, Koppelman GH, Plomin R, Njølstad PR, Dedoussis GD, Froguel P, Sørensen TIA, Jacobsson B, Freathy RM, Zemel BS, Raitakari O, Vrijheid M, Feenstra B, Lyytikäinen LP, Snieder H, Kirsten H, Holt PG, Heinrich J, Widén E, Sunyer J, Boomsma DI, Järvelin MR, Körner A, Davey Smith G, Holm JC, Atalay M, Murray C, Bisgaard H, McCarthy MI, ,Jaddoe VWV, Grant SFA, Felix JF

PLoS Genet. 2020 10;16(10):e1008718

Identifying factors associated with obesity traits in undergraduate students: a scoping review.

Morassut RE, Tian C, Meyre D

Int J Public Health. 2020 09;65(7):1193-1204

Association of AMY1A/AMY2A copy numbers and AMY1/AMY2 serum enzymatic activity with obesity in Mexican children.

Vázquez-Moreno M, Mejía-Benítez A, Sharma T, Peralta-Romero J, Locia-Morales D, Klünder-Klünder M, ,Cruz M, Meyre D

Pediatr Obes. 2020 08;15(8):e12641

Causal Association of Haptoglobin With Obesity in Mexican Children: A Mendelian Randomization Study.

Vázquez-Moreno M, Locia-Morales D, Perez-Herrera A, Gomez-Diaz RA, Gonzalez-Dzib R, Valdez-González AL, Flores-Alfaro E, Corona-Salazar P, Suarez-Sanchez F, Gomez-Zamudio J, Valladares-Salgado A, Wacher-Rodarte N, Cruz M, Meyre D

J Clin Endocrinol Metab. 2020 07 1;105(7):

Medium term post-bariatric surgery deficit of vitamin B12 is predicted by deficit at time of surgery.

Antoine D, Li Z, Quilliot D, Sirveaux MA, Meyre D, Mangeon A, Brunaud L, Guéant JL, Guéant-Rodriguez RM

Clin Nutr. 2020 Apr 25;:

Summer Season and Recommended Vitamin D Intake Support Adequate Vitamin D Status throughout Pregnancy in Healthy Canadian Women and Their Newborns.

Perreault M, Atkinson SA, Meyre D, Fusch G, Mottola MF,

J Nutr. 2020 04 1;150(4):739-746

The Melanocortin 4 Receptor p.Ile269Asn Mutation Is Associated with Childhood and Adult Obesity in Mexicans.

Vázquez-Moreno M, Zeng H, Locia-Morales D, Peralta-Romero J, Asif H, Maharaj A, Tam V, Romero-Figueroa MDS, Sosa-Bustamante GP, Méndez-Martínez S, Mejía-Benítez A, Valladares-Salgado A, Wacher-Rodarte N, ,Cruz M, Meyre D

J Clin Endocrinol Metab. 2020 04 1;105(4):

Zinc Supplementation and Body Weight: A Systematic Review and Dose-Response Meta-analysis of Randomized Controlled Trials.

Abdollahi S, Toupchian O, Jayedi A, Meyre D, Tam V, Soltani S

Adv Nutr. 2020 03 1;11(2):398-411

Association between impulsivity traits and body mass index at the observational and genetic epidemiology level.

Meyre D, Mohamed S, Gray JC, Weafer J, MacKillop J, de Wit H

Sci Rep. 2019 11 26;9(1):17583

Contribution of rare coding mutations in CD36 to type 2 diabetes and cardio-metabolic complications.

Meyre D, Andress EJ, Sharma T, Snippe M, Asif H, Maharaj A, Vatin V, Gaget S, Besnard P, Choquet H, Froguel P, Linton KJ

Sci Rep. 2019 11 20;9(1):17123

Deficits in executive function and suppression of default mode network in obesity.

Syan SK, Owens MM, Goodman B, Epstein LH, Meyre D, Sweet LH, MacKillop J

Neuroimage Clin. 2019 10 26;24:102015

Allelic frequency differences of variants between Caucasians and Asians and their association with major mood disorders.

Yang Z, Zhang S, Zhang F, Yao Y, Kim K, Meyre D, Zhang H, Liao H, Rao S, Huang X

Signal Transduct Target Ther. 2019 10 4;4:39

A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity.

Bradfield JP, Vogelezang S, Felix JF, Chesi A, Helgeland Ø, Horikoshi M, Karhunen V, Lowry E, Cousminer DL, Ahluwalia TS, Thiering E, Boh ET, Zafarmand MH, Vilor-Tejedor N, Wang CA, Joro R, Chen Z, Gauderman WJ, Pitkänen N, Parra EJ, Fernandez-Rhodes L, Alyass A, Monnereau C, Curtin JA, Have CT, McCormack SE, Hollensted M, Frithioff-Bøjsøe C, Valladares-Salgado A, Peralta-Romero J, Teo YY, Standl M, Leinonen JT, Holm JC, Peters T, Vioque J, Vrijheid M, Simpson A, Custovic A, Vaudel M, Canouil M, Lindi V, Atalay M, Kähönen M, Raitakari OT, van Schaik BDC, Berkowitz RI, Cole SA, Voruganti VS, Wang Y, Highland HM, Comuzzie AG, Butte NF, Justice AE, Gahagan S, Blanco E, Lehtimäki T, Lakka TA, Hebebrand J, Bonnefond A, Grarup N, Froguel P, Lyytikäinen LP, Cruz M, Kobes S, Hanson RL, Zemel BS, Hinney A, Teo KK, Meyre D, North KE, Gilliland FD, Bisgaard H, Bustamante M, Bonnelykke K, Pennell CE, Rivadeneira F, Uitterlinden AG, Baier LJ, Vrijkotte TGM, Heinrich J, Sørensen TIA, Saw SM, Pedersen O, Hansen T, Eriksson J, Widén E, McCarthy MI, Njølstad PR, Power C, Hyppönen E, Sebert S, Brown CD, Järvelin MR, Timpson NJ, Johansson S, Hakonarson H, Jaddoe VWV, ,Grant SFA

Hum Mol Genet. 2019 10 1;28(19):3327-3338

Benefits and limitations of genome-wide association studies.

Tam V, Patel N, Turcotte M, Bossé Y, Paré G, Meyre D

Nat Rev Genet. 2019 08;20(8):467-484

Loss-of-function mutations in the melanocortin-3 receptor gene confer risk for human obesity: A systematic review and meta-analysis.

Ehtesham S, Qasim A, Meyre D

Obes Rev. 2019 08;20(8):1085-1092

A Candidate-Gene Approach Identifies Novel Associations Between Common Variants in/Near Syndromic Obesity Genes and BMI in Pediatric and Adult European Populations.

Wang DX, Kaur Y, Alyass A, Meyre D

Diabetes. 2019 04;68(4):724-732

Comprehensive identification of pleiotropic loci for body fat distribution using the NHGRI-EBI Catalog of published genome-wide association studies.

Kaur Y, Wang DX, Liu HY, Meyre D

Obes Rev. 2019 03;20(3):385-406

Adiponectin is associated with cardio-metabolic traits in Mexican children.

He J, Stryjecki C, Reddon H, Peralta-Romero J, Karam-Araujo R, Suarez F, Gomez-Zamudio J, Burguete-Garcia A, Alyass A, Cruz M, Meyre D

Sci Rep. 2019 02 28;9(1):3084

Established and emerging strategies to crack the genetic code of obesity.

Tam V, Turcotte M, Meyre D

Obes Rev. 2019 02;20(2):212-240

Fine-mapping of 98 obesity loci in Mexican children.

Liu HY, Alyass A, Abadi A, Peralta-Romero J, Suarez F, Gomez-Zamudio J, Audirac A, Parra EJ, Cruz M, Meyre D

Int J Obes (Lond). 2019 01;43(1):23-32

Gain-of-function variants in the melanocortin 4 receptor gene confer susceptibility to binge eating disorder in subjects with obesity: a systematic review and meta-analysis.

Qasim A, Mayhew AJ, Ehtesham S, Alyass A, Volckmar AL, Herpertz S, Hinney A, Hebebrand J, Meyre D

Obes Rev. 2019 01;20(1):13-21

Genetic contribution to waist-to-hip ratio in Mexican children and adolescents based on 12 loci validated in European adults.

Turcotte M, Abadi A, Peralta-Romero J, Suarez F, Reddon H, Gomez-Zamudio J, Burguete-Garcia AI, Cruz M, Meyre D

Int J Obes (Lond). 2019 01;43(1):13-22

Structured diet and exercise guidance in pregnancy to improve health in women and their offspring: study protocol for the Be Healthy in Pregnancy (BHIP) randomized controlled trial.

Perreault M, Atkinson SA, Mottola MF, Phillips SM, Bracken K, Hutton EK, Xie F, Meyre D, Morassut RE, Prapavessis H, Thabane L,

Trials. 2018 12 19;19(1):691

Revisiting the evolutionary origins of obesity: lazy versus peppy-thrifty genotype hypothesis.

Reddon H, Patel Y, Turcotte M, Pigeyre M, Meyre D

Obes Rev. 2018 11;19(11):1525-1543

Blood CSF1 and CXCL12 as Causal Mediators of Coronary Artery Disease.

Sjaarda J, Gerstein H, Chong M, Yusuf S, Meyre D, Anand SS, Hess S, Paré G

J Am Coll Cardiol. 2018 07 17;72(3):300-310

The Extending Spectrum of NPC1-Related Human Disorders: From Niemann-Pick C1 Disease to Obesity.

Lamri A, Pigeyre M, Garver WS, Meyre D

Endocr Rev. 2018 04 1;39(2):192-220

Exploring metabolic factors and health behaviors in relation to suicide attempts: A case-control study.

Perera S, Eisen RB, Bhatt M, Dennis BB, Bawor M, El-Sheikh W, DeJesus J, Rangarajan S, Sholer H, Iordan E, Mackie P, Islam S, Dehghan M, Brasch J, Meyre D, de Souza R, Thabane L, Samaan Z

J Affect Disord. 2018 03 15;229:386-395

Obesity genetics: insights from the Pakistani population.

Pigeyre M, Saqlain M, Turcotte M, Raja GK, Meyre D

Obes Rev. 2018 03;19(3):364-380

Parental and child genetic contributions to obesity traits in early life based on 83 loci validated in adults: the FAMILY study.

Li A, Robiou-du-Pont S, Anand SS, Morrison KM, McDonald SD, Atkinson SA, Teo KK, Meyre D

Pediatr Obes. 2018 03;13(3):133-140

On the origin of obesity: identifying the biological, environmental and cultural drivers of genetic risk among human populations.

Qasim A, Turcotte M, de Souza RJ, Samaan MC, Champredon D, Dushoff J, Speakman JR, Meyre D

Obes Rev. 2018 02;19(2):121-149

Ethnic and population differences in the genetic predisposition to human obesity.

Stryjecki C, Alyass A, Meyre D

Obes Rev. 2018 01;19(1):62-80

Rationale and design of GENEiUS: a prospective observational study on the genetic and environmental determinants of body mass index evolution in Canadian undergraduate students.

Morassut RE, Langlois C, Alyass A, Ishola AF, Yazdi FT, Mayhew AJ, Reddon H, MacKillop J, Pigeyre M, Meyre D

BMJ Open. 2017 12 10;7(12):e019365

Penetrance of Polygenic Obesity Susceptibility Loci across the Body Mass Index Distribution.

Abadi A, Alyass A, Robiou du Pont S, Bolker B, Singh P, Mohan V, Diaz R, Engert JC, Yusuf S, Gerstein HC, Anand SS, Meyre D

Am J Hum Genet. 2017 12 7;101(6):925-938

Give GWAS a Chance.

Meyre D

Diabetes. 2017 11;66(11):2741-2742

Helicobacter pylori colonization and obesity - a Mendelian randomization study.

den Hollander WJ, Broer L, Schurmann C, Meyre D, den Hoed CM, Mayerle J, Hofman A, Homuth G, Uitterlinden AG, Lerch MM, Kuipers EJ

Sci Rep. 2017 10 31;7(1):14467

An Evolutionary Genetic Perspective of Eating Disorders.

Mayhew AJ, Pigeyre M, Couturier J, Meyre D

Neuroendocrinology. 2017 10 24;106(3):292-306

Parental and offspring contribution of genetic markers of adult blood pressure in early life: The FAMILY study.

Robiou-du-Pont S, Anand SS, Morrison KM, McDonald SD, Atkinson SA, Teo KK, Meyre D

PLoS One. 2017 10 18;12(10):e0186218

A systematic survey of the methods literature on the reporting quality and optimal methods of handling participants with missing outcome data for continuous outcomes in randomized controlled trials.

Zhang Y, Alyass A, Vanniyasingam T, Sadeghirad B, Flórez ID, Pichika SC, Kennedy SA, Abdulkarimova U, Zhang Y, Iljon T, Morgano GP, Colunga Lozano LE, Aloweni FAB, Lopes LC, Yepes-Nuñez JJ, Fei Y, Wang L, Kahale LA, Meyre D, Akl EA, Thabane L, Guyatt GH

J Clin Epidemiol. 2017 08;88:67-80

APOA5 and APOA1 polymorphisms are associated with triglyceride levels in Mexican children.

Suárez-Sánchez F, Klunder-Klunder M, Valladares-Salgado A, Gómez-Zamudio J, Peralta-Romero J, Meyre D, Burguete-García A, Cruz M

Pediatr Obes. 2017 08;12(4):330-336

Assessing the Heritability of Complex Traits in Humans: Methodological Challenges and Opportunities.

Mayhew AJ, Meyre D

Curr Genomics. 2017 08;18(4):332-340

Physical Activity and Global Self-worth in a Longitudinal Study of Children.

Reddon H, Meyre D, Cairney J

Med Sci Sports Exerc. 2017 08;49(8):1606-1613

The Niemann-Pick C1 gene interacts with a high-fat diet to promote weight gain through differential regulation of central energy metabolism pathways.

Castillo JJ, Jelinek D, Wei H, Gannon NP, Vaughan RA, Horwood LJ, Meaney FJ, Garcia-Smith R, Trujillo KA, Heidenreich RA, Meyre D, Orlando RA, LeBoeuf RC, Garver WS

Am J Physiol Endocrinol Metab. 2017 08 1;313(2):E183-E194

Folate and vitamin B12 status is associated with insulin resistance and metabolic syndrome in morbid obesity.

Li Z, Gueant-Rodriguez RM, Quilliot D, Sirveaux MA, Meyre D, Gueant JL, Brunaud L

Clin Nutr. 2017 Jul;:

A systematic review of genetic syndromes with obesity.

Kaur Y, de Souza RJ, Gibson WT, Meyre D

Obes Rev. 2017 06;18(6):603-634

Influence of depression on genetic predisposition to type 2 diabetes in a multiethnic longitudinal study.

Garasia S, Samaan Z, Gerstein HC, Engert JC, Mohan V, Diaz R, Anand SS, Meyre D

Sci Rep. 2017 05 9;7(1):1629

Genetic contribution to lipid levels in early life based on 158 loci validated in adults: the FAMILY study.

Christie S, Robiou-du-Pont S, Anand SS, Morrison KM, McDonald SD, Paré G, Atkinson SA, Teo KK, Meyre D

Sci Rep. 2017 03 6;7(1):68

Genetic association of rs1344706 in ZNF804A with bipolar disorder and schizophrenia susceptibility in Chinese populations.

Rao S, Yao Y, Ryan J, Jin C, Xu Y, Huang X, Guo J, Wen Y, Mao C, Meyre D, Zhang F

Sci Rep. 2017 01 25;7:41140

A genetic link between prepregnancy body mass index, postpartum weight retention, and offspring weight in early childhood.

Li A, Teo KK, Morrison KM, McDonald SD, Atkinson SA, Anand SS, Meyre D

Obesity (Silver Spring). 2017 01;25(1):236-243

Evaluating the transferability of 15 European-derived fasting plasma glucose SNPs in Mexican children and adolescents.

Langlois C, Abadi A, Peralta-Romero J, Alyass A, Suarez F, Gomez-Zamudio J, Burguete-Garcia AI, Yazdi FT, Cruz M, Meyre D

Sci Rep. 2016 10 26;6:36202

Interaction between GPR120 p.R270H loss-of-function variant and dietary fat intake on incident type 2 diabetes risk in the D.E.S.I.R. study.

Lamri A, Bonnefond A, Meyre D, Balkau B, Roussel R, Marre M, Froguel P, Fumeron F,

Nutr Metab Cardiovasc Dis. 2016 10;26(10):931-6

Assessing the effects of 35 European-derived BMI-associated SNPs in Mexican children.

Abadi A, Peralta-Romero J, Suarez F, Gomez-Zamudio J, Burguete-Garcia AI, Cruz M, Meyre D

Obesity (Silver Spring). 2016 09;24(9):1989-95

Common variants in CACNA1C and MDD susceptibility: A comprehensive meta-analysis.

Rao S, Yao Y, Zheng C, Ryan J, Mao C, Zhang F, Meyre D, Xu Q

Am J Med Genet B Neuropsychiatr Genet. 2016 09;171(6):896-903

The importance of gene-environment interactions in human obesity.

Reddon H, Guéant JL, Meyre D

Clin. Sci.. 2016 Sep;130(18):1571-97

Longitudinal relationships between glycemic status and body mass index in a multiethnic study: evidence from observational and genetic epidemiology.

Ishola AF, Gerstein HC, Engert JC, Mohan V, Diaz R, Anand SS, Meyre D

Sci Rep. 2016 08 2;6:30744

Eating Behavior, Low-Frequency Functional Mutations in the Melanocortin-4 Receptor (MC4R) Gene, and Outcomes of Bariatric Operations: A 6-Year Prospective Study.

Bonnefond A, Keller R, Meyre D, Stutzmann F, Thuillier D, Stefanov DG, Froguel P, Horber FF, Kral JG

Diabetes Care. 2016 08;39(8):1384-92

Empirical evaluation of the Q-Genie tool: a protocol for assessment of effectiveness.

Sohani ZN, Sarma S, Alyass A, de Souza RJ, Robiou-du-Pont S, Li A, Mayhew A, Yazdi F, Reddon H, Lamri A, Stryjecki C, Ishola A, Lee YK, Vashi N, Anand SS, Meyre D

BMJ Open. 2016 06 9;6(6):e010403

Recent progress in genetics, epigenetics and metagenomics unveils the pathophysiology of human obesity.

Pigeyre M, Yazdi FT, Kaur Y, Meyre D

Clin Sci (Lond). 2016 06 1;130(12):943-86

Association between PPAR-γ2 Pro12Ala genotype and insulin resistance is modified by circulating lipids in Mexican children.

Stryjecki C, Peralta-Romero J, Alyass A, Karam-Araujo R, Suarez F, Gomez-Zamudio J, Burguete-Garcia A, Cruz M, Meyre D

Sci Rep. 2016 04 14;6:24472

Risk Alleles in/near ADCY5, ADRA2A, CDKAL1, CDKN2A/B, GRB10, and TCF7L2 Elevate Plasma Glucose Levels at Birth and in Early Childhood: Results from the FAMILY Study.

Sohani ZN, Anand SS, Robiou-du-Pont S, Morrison KM, McDonald SD, Atkinson SA, Teo KK, Meyre D

PLoS One. 2016 04 6;11(4):e0152107

A systematic review and meta-analysis of nut consumption and incident risk of CVD and all-cause mortality.

Mayhew AJ, de Souza RJ, Meyre D, Anand SS, Mente A

Br J Nutr. 2016 01 28;115(2):212-25

Physical activity and genetic predisposition to obesity in a multiethnic longitudinal study.

Reddon H, Gerstein HC, Engert JC, Mohan V, Bosch J, Desai D, Bailey SD, Diaz R, Yusuf S, Anand SS, Meyre D

Sci Rep. 2016 01 4;6:18672

Obesity genes and risk of major depressive disorder in a multiethnic population: a cross-sectional study.

Samaan Z, Lee YK, Gerstein HC, Engert JC, Bosch J, Mohan V, Diaz R, Yusuf S, Anand SS, Meyre D,

J Clin Psychiatry. 2015 12;76(12):e1611-8

Lack of association between type 2 diabetes and major depression: epidemiologic and genetic evidence in a multiethnic population.

Samaan Z, Garasia S, Gerstein HC, Engert JC, Mohan V, Diaz R, Anand SS, Meyre D

Transl Psychiatry. 2015 08 11;5(8):e618

From big data analysis to personalized medicine for all: challenges and opportunities.

Alyass A, Turcotte M, Meyre D

BMC Med Genomics. 2015 06 27;8:33

Contribution of common non-synonymous variants in PCSK1 to body mass index variation and risk of obesity: a systematic review and meta-analysis with evidence from up to 331 175 individuals.

Nead KT, Li A, Wehner MR, Neupane B, Gustafsson S, Butterworth A, Engert JC, Davis AD, Hegele RA, Miller R, den Hoed M, Khaw KT, Kilpeläinen TO, Wareham N, Edwards TL, Hallmans G, Varga TV, Kardia SL, Smith JA, Zhao W, Faul JD, Weir D, Mi J, Xi B, Quinteros SC, Cooper C, Sayer AA, Jameson K, Grøntved A, Fornage M, Sidney S, Hanis CL, Highland HM, Häring HU, Heni M, Lasky-Su J, Weiss ST, Gerhard GS, Still C, Melka MM, Pausova Z, Paus T, Grant SF, Hakonarson H, Price RA, Wang K, Scherag A, Hebebrand J, Hinney A, ,Franks PW, Frayling TM, McCarthy MI, Hirschhorn JN, Loos RJ, Ingelsson E, Gerstein HC, Yusuf S, Beyene J, Anand SS, Meyre D

Hum Mol Genet. 2015 06 15;24(12):3582-94