Fiche publication
Date publication
juillet 2018
Journal
Journal of the American College of Cardiology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr MEYRE David
Tous les auteurs :
Sjaarda J, Gerstein H, Chong M, Yusuf S, Meyre D, Anand SS, Hess S, Paré G
Lien Pubmed
Résumé
Identification of biomarkers that cause coronary artery disease (CAD) has led to important advances in prevention and treatment. Epidemiological analyses have identified many biomarker-CAD relationships; however, these associations may arise from reverse causation and/or confounding and therefore may not represent true causal associations. Mendelian randomization (MR) analyses overcome these limitations.
Mots clés
CSF1, CXCL12, Mendelian randomization, biomarker, coronary artery disease, genetics
Référence
J Am Coll Cardiol. 2018 07 17;72(3):300-310
