EN DE

Dr BEFORT Katia

Fiche personne

coordonnées

LNCA
12 rue Goethe
67000 STRASBOURG

03 68 85 20 09

katia.befort@unistra.fr

Territoire

Alsace

Statut

Chercheur

affiliation

Université de Strasbourg (Unistra)

équipes/plateformes

Equipe Laboratoire de neurosciences cognitives et adaptatives UMR 7364

Recherche

Thématique de recherche :

Neuroadaptations comportementales et moléculaires, et notamment épigénétiques, apparaissant dans les conduites addictives, qu’elles concernent la consommation de drogues ou celle abusive d’aliments palatables.

Projets

Consommation excessive de sucre : facteur de risque pour l’abus d’alcool ?

2021 - Porteur du projet : Dr BEFORT Katia

Publications

The rostromedial tegmental nucleus gates fat overconsumption through ventral tegmental area output in male rats.

Schoukroun F, Befort K, Bourdy R

Neuropsychopharmacology. 2024 04 3;:

Altered reward processing following sucrose bingeing in male and female mice.

Awad G, Aubry AS, Olmstead MC, Befort K

Nutr Neurosci. 2024 03 15;:1-14

The Role of the Endocannabinoid System in Binge Eating Disorder.

Bourdy R, Befort K

Int J Mol Sci. 2023 05 31;24(11):

Hippocampal Cannabinoid 1 Receptors Are Modulated Following Cocaine Self-administration in Male Rats.

De Sa Nogueira D, Bourdy R, Alcala-Vida R, Filliol D, Andry V, Goumon Y, Zwiller J, Romieu P, Merienne K, Olmstead MC, Befort K

Mol Neurobiol. 2022 Jan 15;:

LSP2-9166, an orthosteric mGlu4 and mGlu7 receptor agonist, reduces cocaine self-administration under a progressive ratio schedule in rats.

De Sa Nogueira D, Bourdy R, Filliol D, Quessada C, McCort-Tranchepain I, Acher F, Zwiller J, Romieu P, Befort K

Neurosci Lett. 2021 11 1;764:135603

Binge sucrose-induced neuroadaptations: A focus on the endocannabinoid system.

de Sa Nogueira D, Bourdy R, Filliol D, Awad G, Andry V, Goumon Y, Olmstead MC, Befort K

Appetite. 2021 09 1;164:105258

The endocannabinoid system is modulated in reward and homeostatic brain regions following diet-induced obesity in rats: a cluster analysis approach.

Bourdy R, Hertz A, Filliol D, Andry V, Goumon Y, Mendoza J, Olmstead MC, Befort K

Eur J Nutr. 2021 Jun 24;:

Hippocampal mu opioid receptors are modulated following cocaine self-administration in rat.

De Sa Nogueira D, Bourdy R, Filliol D, Romieu P, Befort K

Eur J Neurosci. 2021 05;53(10):3341-3349

Can cocaine-induced neuroinflammation explain maladaptive cocaine-associated memories?

Correia C, Romieu P, Olmstead MC, Befort K

Neurosci Biobehav Rev. 2020 04;111:69-83

Deletion of mu opioid receptors reduces palatable solution intake in a mouse model of binge eating.

Awad G, Roeckel LA, Massotte D, Olmstead MC, Befort K

Behav Pharmacol. 2020 04;31(2&3):249-255

La Société de Biologie de Strasbourg : 100 ans au service de la science et de la société

Antony P, Fournel S, Zoll J, Mantz JM, Befort K, Massotte D, Giégé P, Céraline J, Metzger D, Becker H, Drouard L, Florentz C, Martin R, Nébigil C, Potier S, Schaefer A, Schaeffer E, Schuster C, Bresson A, Quéméneur E, Choulier L, Matt N, Monassier L, Lugnier C, Freysz L, Hoffmann J, Dreyfus H, Romier C

Biol Aujourdhui. 2020 ;214(3-4):137-148

Addiction: A neurobiological and cognitive brain disorder.

Massotte D, Lalanne-Tongio L, Befort K

Neurosci Biobehav Rev. 2019 11;106:1-2

Neuroepigenetics and addictive behaviors: Where do we stand?

De Sa Nogueira D, Merienne K, Befort K

Neurosci Biobehav Rev. 2019 11;106:58-72

CB1 Agonism Alters Addiction-Related Behaviors in Mice Lacking Mu or Delta Opioid Receptors.

Roeckel LA, Massotte D, Olmstead MC, Befort K

Front Psychiatry. 2018 11 27;9:630

Kappa opioid receptor antagonism and chronic antidepressant treatment have beneficial activities on social interactions and grooming deficits during heroin abstinence.

Lalanne L, Ayranci G, Filliol D, Gavériaux-Ruff C, Befort K, Kieffer BL, Lutz PE

Addict Biol. 2017 07;22(4):1010-1021

Mu Opioid Receptors in Gamma-Aminobutyric Acidergic Forebrain Neurons Moderate Motivation for Heroin and Palatable Food.

Charbogne P, Gardon O, Martín-García E, Keyworth HL, Matsui A, Mechling AE, Bienert T, Nasseef MT, Robé A, Moquin L, Darcq E, Ben Hamida S, Robledo P, Matifas A, Befort K, Gavériaux-Ruff C, Harsan LA, von Elverfeldt D, Hennig J, Gratton A, Kitchen I, Bailey A, Alvarez VA, Maldonado R, Kieffer BL

Biol Psychiatry. 2017 05 1;81(9):778-788

Inhibition of DNA methyltransferases regulates cocaine self-administration by rats: a genome-wide DNA methylation study.

Fonteneau M, Filliol D, Anglard P, Befort K, Romieu P, Zwiller J

Genes Brain Behav. 2017 03;16(3):313-327

Dissociation of heroin-induced emotional dysfunction from psychomotor activation and physical dependence among inbred mouse strains.

Ayranci G, Befort K, Lalanne L, Kieffer BL, Lutz PE

Psychopharmacology (Berl). 2015 06;232(11):1957-71

A novel anxiogenic role for the delta opioid receptor expressed in GABAergic forebrain neurons.

Chu Sin Chung P, Keyworth HL, Martin-Garcia E, Charbogne P, Darcq E, Bailey A, Filliol D, Matifas A, Scherrer G, Ouagazzal AM, Gaveriaux-Ruff C, Befort K, Maldonado R, Kitchen I, Kieffer BL

Biol Psychiatry. 2015 02 15;77(4):404-15

Interactions of the opioid and cannabinoid systems in reward: Insights from knockout studies.

Befort K

Front Pharmacol. 2015 02 5;6:6

Delta opioid receptors expressed in forebrain GABAergic neurons are responsible for SNC80-induced seizures.

Chung PC, Boehrer A, Stephan A, Matifas A, Scherrer G, Darcq E, Befort K, Kieffer BL

Behav Brain Res. 2015 02 1;278:429-34

Distinct mu, delta, and kappa opioid receptor mechanisms underlie low sociability and depressive-like behaviors during heroin abstinence.

Lutz PE, Ayranci G, Chu-Sin-Chung P, Matifas A, Koebel P, Filliol D, Befort K, Ouagazzal AM, Kieffer BL

Neuropsychopharmacology. 2014 Oct;39(11):2694-705