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Engineering stable wax-based w/O/W double emulsions for high-payload encapsulation, osmotic resistance, and temperature-activated permeability.
Elhassan M, Conzatti G, Anton H, Collot M, Vandamme T, Anton N
Int J Pharm. 2026 02 21;:126713
SBIS, a new orange fluorescent vital probe for the 4D imaging of brown algal cells.
Zilliox M, Collot M, Charrier B
J Cell Sci. 2025 10 1;138(19):
Optimized Fluorescent pH-Sensitive Dextran Conjugates Enable Ratiometric Measurement of Cerebral Blood pH In Vivo and In Situ.
Walter S, Tournissac M, Chaigneau E, Charpak S, Collot M
ACS Appl Mater Interfaces. 2025 08 13;17(32):45501-45510
A Photoactivatable Plasma Membrane Probe Based on a Self-Triggered Photooxidation Cascade for Live Cell Super-Resolution Microscopy.
Pfister S, Le Berruyer V, Fam K, Collot M
Angew Chem Int Ed Engl. 2025 06 10;64(24):e202425276
Spontaneously blinking spiroamide rhodamines for live SMLM imaging of the plasma membrane.
Pfister S, Walter S, Perrier A, Collot M
Chem Commun (Camb). 2025 04 17;61(33):6170-6173
Lipophilic molecular rotor to assess the viscosity of oil core in nano-emulsion droplets.
Elhassan M, Faivre C, Anton H, Conzatti G, Didier P, Vandamme T, Elamin AS, Collot M, Anton N
Soft Matter. 2025 01 20;:
(E, E)-farnesol and myristic acid-loaded lipid nanoparticles overcome colistin resistance in Acinetobacter baumannii.
Faivre C, Imtiyaz FD, Buyck JM, Marchand S, Marcotte M, Henry T, Anton N, Collot M, Tewes F
Int J Pharm. 2024 12 25;667(Pt A):124907
Targeted Photoactivatable Green-Emitting BODIPY Based on Directed Photooxidation-Induced Activation and its Application to Live Dynamic Super-Resolution Microscopy.
Saladin L, Le Berruyer V, Bonnevial M, Didier P, Collot M
Chemistry. 2024 10 4;:e202403409
Neurovascular coupling and CO interrogate distinct vascular regulations.
Tournissac M, Chaigneau E, Pfister S, Aydin AK, Goulam Houssen Y, O'Herron P, Filosa J, Collot M, Joutel A, Charpak S
Nat Commun. 2024 09 2;15(1):7635
Red-Emitting Pyrrolyl Squaraine Molecular Rotor Reports Variations of Plasma Membrane and Vesicular Viscosity in Fluorescence Lifetime Imaging.
Pfister S, Lesieur J, Bourdoncle P, Elhassan M, Didier P, Anton N, Anton H, Collot M
Anal Chem. 2024 07 27;:
Quantum Dot-Based FRET Nanosensors for Talin-Membrane Assembly and Mechanosensing.
Ntadambanya A, Pernier J, David V, Susumu K, Medintz IL, Collot M, Klymchenko A, Hildebrandt N, Le Potier I, Le Clainche C, Cardoso Dos Santos M
Angew Chem Int Ed Engl. 2024 07 15;:e202409852
Targeted Photoconvertible BODIPYs Based on Directed Photooxidation-Induced Conversion for Applications in Photoconversion and Live Super-Resolution Imaging.
Saladin L, Breton V, Le Berruyer V, Nazac P, Lequeu T, Didier P, Danglot L, Collot M
J Am Chem Soc. 2024 06 11;:
Fluorescent styrenes for mitochondrial imaging and viscosity sensing.
Singh D, Ghorpade M, Regar R, Collot M, Soppina V, Kanvah S
Photochem Photobiol. 2024 02 22;100(4):936-945
Development of nanoparticles based on amphiphilic cyclodextrins for the delivery of active substances.
Augis L, Nerbø Reiten I, Førde JL, Casas-Solvas JM, Sizun C, Bizien T, Rajkovic I, Larquet E, Michelet A, Collot M, Lesieur S, Herfindal L, Legrand FX
Int J Pharm. 2024 02 15;651:123723
Tuning Directed Photooxidation-Induced Conversion of Pyrrole-Based Styryl Coumarin Dual-Color Photoconverters.
Saladin L, Dal Pra O, Klymchenko AS, Didier P, Collot M
Chemistry. 2023 03 15;:e202300685
Tuning Directed Photooxidation Induced Conversion of Pyrrole-based Styryl Coumarins Dual-Color Photoconverters.
Saladin L, Dal Pra O, Klymchenko A, Didier P, Collot M
Chemistry. 2023 01 31;:
Dual-Color Photoconvertible Fluorescent Probes Based on Directed Photooxidation Induced Conversion for bioimaging.
Saladin L, Breton V, Dal Pra O, Klymchenko AS, Danglot L, Didier P, Collot M
Angew Chem Int Ed Engl. 2022 11 24;:
A Conjugate between Lqh-8/6, a Natural Peptide Analogue of Chlorotoxin, and Doxorubicin Efficiently Induces Glioma Cell Death.
Dardevet L, Najlaoui F, Aroui S, Collot M, Tisseyre C, Pennington MW, Mallet JM, De Waard M
Biomedicines. 2022 10 17;10(10):
Advanced functional fluorescent probes for cell plasma membranes.
Collot M, Pfister S, Klymchenko AS
Curr Opin Chem Biol. 2022 08;69:102161
Rational Design of Self-Quenched Rhodamine Dimers as Fluorogenic Aptamer Probes for Live-Cell RNA Imaging.
Fam KT, Pelletier R, Bouhedda F, Ryckelynck M, Collot M, Klymchenko AS
Anal Chem. 2022 Apr 29;:
Imaging and Measuring Vesicular Acidification with a Plasma Membrane-Targeted Ratiometric pH Probe.
Michelis S, Danglot L, Vauchelles R, Klymchenko AS, Collot M
Anal Chem. 2022 Apr 4;:
Probing Variations of Reduction Activity at the Plasma Membrane Using a Targeted Ratiometric FRET Probe.
Mukherjee T, Kanvah S, Klymchenko AS, Collot M
ACS Appl Mater Interfaces. 2021 Aug 23;:
Confronting molecular rotors and self-quenched dimers as fluorogenic BODIPY systems to probe biotin receptors in cancer cells.
Fam KT, Saladin L, Klymchenko AS, Collot M
Chem Commun (Camb). 2021 May 13;57(39):4807-4810
µIVC-Useq: a microfluidic-assisted high-throughput functionnal screening in tandem with next generation sequencing and artificial neural network to rapidly characterize RNA molecules.
Cubi R, Bouhedda F, Collot M, Klymchenko AS, Ryckelynck M
RNA. 2021 May 5;:
Fluorescent labeling of biocompatible block copolymers: synthetic strategies and applications in bioimaging.
Bou S, Klymchenko AS, Collot M
Mater Adv. 2021 Apr 6;2(10):3213-3233
Ultrabright Green-Emitting Nanoemulsions Based on Natural Lipids-BODIPY Conjugates.
Wang X, Bou S, Klymchenko AS, Anton N, Collot M
Nanomaterials (Basel). 2021 Mar 23;11(3):
Fluorescent nanocarriers targeting VCAM-1 for early detection of senescent endothelial cells.
Belcastro E, Rehman AU, Remila L, Park SH, Gong DS, Anton N, Auger C, Lefebvre O, Goetz JG, Collot M, Klymchenko AS, Vandamme TF, Schini-Kerth VB
Nanomedicine. 2021 Mar 10;:102379
Fluorogenic squaraine dendrimers for background-free imaging of integrin receptors in cancer cells.
Ashokkumar P, Collot M, Klymchenko AS
Chemistry. 2021 Feb 10;:
Live-cell imaging of the nucleolus and mapping mitochondrial viscosity with a dual function fluorescent probe.
Mukherjee T, Soppina V, Ludovic R, Mély Y, Klymchenko AS, Collot M, Kanvah S
Org Biomol Chem. 2021 Feb 8;:
Recent advances in dioxaborine-based fluorescent materials for bioimaging applications.
Collot M
Mater Horiz. 2021 02 1;8(2):501-514
Tunable functionalization of nano-emulsions using amphiphilic polymers.
Rehman AU, Anton N, Bou S, Schild J, Messaddeq N, Vandamme T, Akram S, Klymchenko A, Collot M
Soft Matter. 2021 Jan 5;:
Dye-Loaded Nanoemulsions: Biomimetic Fluorescent Nanocarriers for Bioimaging and Nanomedicine.
Klymchenko AS, Liu F, Collot M, Anton N
Adv Healthc Mater. 2020 Oct 13;:e2001289
Stealth and Bright Monomolecular Fluorescent Organic Nanoparticles Based on Folded Amphiphilic Polymer.
Collot M, Schild J, Fam KT, Bouchaala R, Klymchenko AS
ACS Nano. 2020 Oct 6;:
Molecular and Functional Diversity of Distinct Subpopulations of the Stressed Insulin-Secreting Cell's Vesiculome.
Giri KR, de Beaurepaire L, Jegou D, Lavy M, Mosser M, Dupont A, Fleurisson R, Dubreil L, Collot M, Van Endert P, Bach JM, Mignot G, Bosch S
Front Immunol. 2020 09 30;11:1814
Ultrabright Fluorescent Polymeric Nanoparticles with Stealth Pluronic Shell for Live Tracking in Mouse Brain.
Khalin I, Heimburger D, Melnychuk N, Collot M, Groschup B, Hellal F, Reisch A, Plesnila N, Klymchenko AS
ACS Nano. 2020 Jul 17;:
Near infrared fluorogenic probe as a prodrug model for evaluating cargo release by nanoemulsions.
Bou S, Wang X, Anton N, Klymchenko AS, Collot M
J Mater Chem B. 2020 Jul 15;8(27):5938-5944
A near-infrared fluorogenic dimer enables background-free imaging of endogenous GPCRs in living mice.
Esteoulle L, Daubeuf F, Collot M, Riché S, Durroux T, Brasse D, Marchand P, Karpenko IA, Klymchenko AS, Bonnet D
Chem Sci. 2020 Jul 14;11(26):6824-6829
Probing biotin receptors in cancer cells with rationally designed fluorogenic squaraine dimers.
Fam KT, Collot M, Klymchenko AS
Chem Sci. 2020 Jul 9;11(31):8240-8248
Further insights into release mechanisms from nano-emulsions, assessed by a simple fluorescence-based method.
Wang X, Collot M, Omran Z, Vandamme TF, Klymchenko A, Anton N
J Colloid Interface Sci. 2020 Jun 11;578:768-778
Lipid-core/polymer-shell hybrid nanoparticles: synthesis and characterization by fluorescence labeling and electrophoresis.
Bou S, Wang X, Anton N, Bouchaala R, Klymchenko AS, Collot M
Soft Matter. 2020 Apr 14;:
Molecular Tuning of Styryl Dyes Leads to Versatile and Efficient Plasma Membrane Probes for Cell and Tissue Imaging.
Collot M, Boutant E, Fam KT, Danglot L, Klymchenko AS
Bioconjug. Chem.. 2020 Feb 13;:
A dimerization-based fluorogenic dye-aptamer module for RNA imaging in live cells.
Bouhedda F, Fam KT, Collot M, Autour A, Marzi S, Klymchenko A, Ryckelynck M
Nat. Chem. Biol.. 2019 Oct 21;:
BODIPY-loaded polymer nanoparticles: chemical structure of cargo defines leakage from nanocarrier in living cells.
Trofymchuk K, Valanciunaite J, Andreiuk B, Reisch A, Collot M, Klymchenko AS
J Mater Chem B. 2019 Aug 28;7(34):5199-5210
A fluorogenic BODIPY molecular rotor as an apoptosis marker.
Ashokkumar P, Ashoka AH, Collot M, Das A, Klymchenko AS
Chem. Commun. (Camb.). 2019 Jun 11;55(48):6902-6905
Optimizing the Fluorescence Properties of Nanoemulsions for Single Particle Tracking in Live Cells.
Wang X, Anton N, Ashokkumar P, Anton H, Fam TK, Vandamme T, Klymchenko AS, Collot M
ACS Appl Mater Interfaces. 2019 Apr 10;11(14):13079-13090
MemBright: A Family of Fluorescent Membrane Probes for Advanced Cellular Imaging and Neuroscience.
Collot M, Ashokkumar P, Anton H, Boutant E, Faklaris O, Galli T, Mély Y, Danglot L, Klymchenko AS
Cell Chem Biol. 2019 Feb 6;:
Probing Polarity and Heterogeneity of Lipid Droplets in Live Cells Using a Push-Pull Fluorophore.
Collot M, Bou S, Fam TK, Richert L, Mély Y, Danglot L, Klymchenko AS
Anal. Chem.. 2019 Feb 5;91(3):1928-1935
Studying the Fate of Tumor Extracellular Vesicles at High Spatiotemporal Resolution Using the Zebrafish Embryo.
Hyenne V, Ghoroghi S, Collot M, Bons J, Follain G, Harlepp S, Mary B, Bauer J, Mercier L, Busnelli I, Lefebvre O, Fekonja N, Garcia-Leon MJ, Machado P, Delalande F, López AA, Silva SG, Verweij FJ, van Niel G, Djouad F, Peinado H, Carapito C, Klymchenko AS, Goetz JG
Dev. Cell. 2019 Feb 4;:
BODIPY with Tuned Amphiphilicity as a Fluorogenic Plasma Membrane Probe.
Collot M, Boutant E, Lehmann M, Klymchenko AS
Bioconjug. Chem.. 2019 01 16;30(1):192-199
Towards the formulation of stable micro and nano double emulsions through silica coating of internal water droplets.
Akram S, Wang X, Vandamme TF, Collot M, Rehman AU, Messaddeq N, Mély Y, Anton N
Langmuir. 2019 Jan 10;:
Recent Advances in Fluorescent Probes for Lipid Droplets.
Fam TK, Klymchenko AS, Collot M
Materials (Basel). 2018 Sep 18;11(9):
Ultrabright and Fluorogenic Probes for Multicolor Imaging and Tracking of Lipid Droplets in Cells and Tissues.
Collot M, Fam TK, Ashokkumar P, Faklaris O, Galli T, Danglot L, Klymchenko AS
J. Am. Chem. Soc.. 2018 04 25;140(16):5401-5411
A new formulation of poly(MAOTIB) nanoparticles as an efficient contrast agent for in vivo X-ray imaging.
Wallyn J, Anton N, Serra CA, Bouquey M, Collot M, Anton H, Weickert JL, Messaddeq N, Vandamme TF
Acta Biomater. 2018 01 15;66:200-212
Turn-on Fluorene Push-Pull Probes with High Brightness and Photostability for Visualizing Lipid Order in Biomembranes.
Shaya J, Collot M, Bénailly F, Mahmoud N, Mély Y, Michel BY, Klymchenko AS, Burger A
ACS Chem. Biol.. 2017 12 15;12(12):3022-3030
PEGylated Red-Emitting Calcium Probe with Improved Sensing Properties for Neuroscience.
Ponsot F, Shen W, Ashokkumar P, Audinat E, Klymchenko AS, Collot M
ACS Sens. 2017 11 22;2(11):1706-1712
A Secondary Structural Element in a Wide Range of Fucosylated Glycoepitopes.
Aeschbacher T, Zierke M, Smieško M, Collot M, Mallet JM, Ernst B, Allain FH, Schubert M
Chemistry. 2017 08 25;23(48):11598-11610
Quantitative assessment of energy transfer in upconverting nanoparticles grafted with organic dyes.
Dukhno O, Przybilla F, Collot M, Klymchenko A, Pivovarenko V, Buchner M, Muhr V, Hirsch T, Mély Y
Nanoscale. 2017 Aug;:
Functionalizing Nanoemulsions with Carboxylates: Impact on the Biodistribution and Pharmacokinetics in Mice.
Attia MF, Dieng SM, Collot M, Klymchenko AS, Bouillot C, Serra CA, Schmutz M, Er-Rafik M, Vandamme TF, Anton N
Macromol Biosci. 2017 07;17(7):
Ca-NIR: a ratiometric near-infrared calcium probe based on a dihydroxanthene-hemicyanine fluorophore.
Collot M, Ponsot F, Klymchenko AS
Chem. Commun. (Camb.). 2017 Jun 1;53(45):6117-6120
Dimerization of the fungal defense lectin CCL2 is essential for its toxicity against nematodes.
Bleuler-Martinez S, Stutz K, Sieber R, Collot M, Mallet JM, Hengartner M, Schubert M, Varrot A, Künzler M
Glycobiology. 2017 05 1;27(5):486-500
Bright fluorogenic squaraines with tuned cell entry for selective imaging of plasma membrane vs. endoplasmic reticulum.
Collot M, Kreder R, Tatarets AL, Patsenker LD, Mely Y, Klymchenko AS
Chem Commun (Camb). 2015 Nov 19;51(96):17136-9
Fluorinated counterion-enhanced emission of rhodamine aggregates: ultrabright nanoparticles for bioimaging and light-harvesting.
Shulov I, Oncul S, Reisch A, Arntz Y, Collot M, Mely Y, Klymchenko AS
Nanoscale. 2015 Oct 29;7(43):18198-210
H-Rubies, a new family of red emitting fluorescent pH sensors for living cells.
Despras G, Zamaleeva AI, Dardevet L, Tisseyre C, Magalhaes JG, Garner C, De Waard M, Amigorena S, Feltz A, Mallet JM, Collot M
Chem Sci. 2015 10 1;6(10):5928-5937
FRET-Based Nanobiosensors for Imaging Intracellular Ca²⁺ and H⁺ Microdomains.
Zamaleeva AI, Despras G, Luccardini C, Collot M, de Waard M, Oheim M, Mallet JM, Feltz A
Sensors (Basel). 2015 09 23;15(9):24662-80
CaRuby-Nano: a novel high affinity calcium probe for dual color imaging.
Collot M, Wilms CD, Bentkhayet A, Marcaggi P, Couchman K, Charpak S, Dieudonné S, Häusser M, Feltz A, Mallet JM
Elife. 2015 03 31;4:
Calcium dynamics in astrocyte processes during neurovascular coupling.
Otsu Y, Couchman K, Lyons DG, Collot M, Agarwal A, Mallet JM, Pfrieger FW, Bergles DE, Charpak S
Nat Neurosci. 2015 02;18(2):210-8
Fluorogenic Squaraine Dimers with Polarity-Sensitive Folding As Bright Far-Red Probes for Background-Free Bioimaging.
Karpenko IA, Collot M, Richert L, Valencia C, Villa P, Mely Y, Hibert M, Bonnet D, Klymchenko AS
J Am Chem Soc. 2014 Dec 29.
New red-fluorescent calcium indicators for optogenetics, photoactivation and multi-color imaging.
Oheim M, van 't Hoff M, Feltz A, Zamaleeva A, Mallet JM, Collot M
Biochim Biophys Acta. 2014 10;1843(10):2284-306
