Détail d'une personne de l'annuaire - fr | Cancéropôle Est, la recherche innovante dans la lutte contre le cancer

Inhibition of Recruitment and Activation of Neutrophils by Pyridazinone-Scaffold-Based Compounds.

Moniot A, Braux J, Siboni R, Guillaume C, Audonnet S, Allart-Simon I, Sapi J, Tirouvanziam R, Gérard S, Gangloff SC, Velard F

Int J Mol Sci. 2022 06 29;23(13):

Pyridazinone Derivatives Limit Osteosarcoma-Cells Growth In Vitro and In Vivo.

Moniot A, Braux J, Bour C, Guillaume C, Lamret F, Allart-Simon I, Audonnet S, Renault S, Rédini F, Laronze-Cochard M, Sapi J, Gangloff SC, Gérard S, Velard F

Cancers (Basel). 2021 Nov 28;13(23):

Conjugates of Ultrasmall Quantum Dots and Acridine Derivatives as Prospective Nanoprobes for Intracellular Investigations.

Linkov P, Samokhvalov P, Baryshnikova M, Laronze-Cochard M, Sapi J, Karaulov A, Nabiev I

Nanomaterials (Basel). 2021 Aug 24;11(9):

Pyridazinone derivatives as potential anti-inflammatory agents: synthesis and biological evaluation as PDE4 inhibitors.

Allart-Simon I, Moniot A, Bisi N, Ponce-Vargas M, Audonnet S, Laronze-Cochard M, Sapi J, Hénon E, Velard F, Gérard S

RSC Med Chem. 2021 Apr 28;12(4):584-592

5-Arylisothiazol-3(2H)-one-1,(1)-(di)oxides: A new class of selective tumor-associated carbonic anhydrases (hCA IX and XII) inhibitors.

Cornelio B, Laronze-Cochard M, Miambo R, De Grandis M, Riccioni R, Borisova B, Dontchev D, Machado C, Ceruso M, Fontana A, Supuran CT, Sapi J

Eur J Med Chem. 2019 Apr 30;175:40-48

Unexpected effect of cyclodepsipeptides bearing a sulfonylhydrazide moiety towards histone deacetylase activity.

Létévé M, Gonzalez C, Moroy G, Martinez A, Jeanblanc J, Legastelois R, Naassila M, Sapi J, Bourguet E

Bioorg. Chem.. 2018 Aug 10;81:222-233

Synthesis and biological evaluation of pyridazinone derivatives as potential anti-inflammatory agents.

Barberot C, Moniot A, Allart-Simon I, Malleret L, Yegorova T, Laronze-Cochard M, Bentaher A, Médebielle M, Bouillon JP, Hénon E, Sapi J, Velard F, Gérard S

Eur J Med Chem. 2018 Feb 25;146:139-146

Structure-Activity Relationships of Benzenesulfonamide-Based Inhibitors towards Carbonic Anhydrase Isoform Specificity.

Bhatt A, Mahon BP, Cruzeiro VW, Cornelio B, Laronze-Cochard M, Ceruso M, Sapi J, Rance GA, Khlobystov AN, Fontana A, Roitberg A, Supuran CT, McKenna R

Chembiochem. 2017 Jan;18(2):213-222

Radical Smiles Rearrangement: An Update.

Allart-Simon I, Gérard S, Sapi J

Molecules. 2016 Jul;21(7):

Design, Synthesis, and Use of MMP-2 Inhibitor-Conjugated Quantum Dots in Functional Biochemical Assays.

Bourguet E, Brazhnik K, Sukhanova A, Moroy G, Brassart-Pasco S, Martin AP, Villena I, Bellon G, Sapi J, Nabiev I

Bioconjug. Chem.. 2016 Apr;27(4):1067-81

4-Arylbenzenesulfonamides as Human Carbonic Anhydrase Inhibitors (hCAIs): Synthesis by Pd Nanocatalyst-Mediated Suzuki-Miyaura Reaction, Enzyme Inhibition, and X-ray Crystallographic Studies.

Cornelio B, Laronze-Cochard M, Ceruso M, Ferraroni M, Rance GA, Carta F, Khlobystov AN, Fontana A, Supuran CT, Sapi J

J. Med. Chem.. 2016 Jan;59(2):721-32

Diastereomer Interconversion via Enolization: A Case Study.

Renzetti A, Di Crescenzo A, Nie F, Bond AD, Gérard S, Sapi J, Fontana A, Villani C

Chirality. 2015 Nov;27(11):779-83

TiCl-promoted condensation of methyl acetoacetate, isobutyraldehyde, and indole: a theoretical and experimental study.

Renzetti A, Marrone A, Gerard S, Sapi J, Nakazawa H, Re N, Fontana A

Phys Chem Chem Phys. 2015 Mar 9.

Interfacing chemical biology and drug discovery: report from the 50th International Conference on Medicinal Chemistry of the SCT (French Medicinal Chemistry Society), July 2-4, 2014, Rouen, France.

Sapi J, Schmidt F, Van Hijfte L, George P

ACS Chem Biol. 2014 Dec 19;9(12):2702-7

Chemical biology: contribution to molecular therapeutic innovation--a new role for chemistry? Report from the thematic symposium organized by the SCT (French Medicinal Chemistry Society), November 26th, 2013.

Schmidt F, George P, Sapi J

ACS Chem Biol. 2014 Apr 18;9(4):849-52

Photochemical aryl radical cyclizations to give (E)-3-ylideneoxindoles.

Gurry M, Allart-Simon I, McArdle P, Gerard S, Sapi J, Aldabbagh F

Molecules. 2014 Sep 30;19(10):15891-9

Cyclopropyl-tryptamine analogues: synthesis and biological evaluation as 5-HT(6) receptor ligands.

Szalata C, Szymoniak J, Fabis F, Butt-Gueulle S, Rault S, Bertus P, Gerard S, Sapi J

ChemMedChem. 2013 Jan;8(1):70-3

Palladium nanoparticles on carbon nanotubes as catalysts of cross-coupling reactions.

Cornelio B, Rance GA, Laronze-Cochard M, Fontana A, Sapi J, Khlobystov AN

J Mater Chem A. 2013;1(31):8737-44.

Neutrophil elastase as a target in lung cancer.

Moroy G, Alix AJ, Sapi J, Hornebeck W, Bourguet E

Anticancer Agents Med Chem. 2012 Jul;12(6):565-79.

First domino radical cyclisation/Smiles rearrangement combination.

Pudlo M, Allart-Simon I, Tinant B, Gerard S, Sapi J

Chem Commun (Camb). 2012 Feb 28;48(18):2442-4

Inhibition of human leukocyte elastase, plasmin and matrix metalloproteinases by oleic acid and oleoyl-galardin derivative(s).

Moroy G, Bourguet E, Decarme M, Sapi J, Alix AJ, Hornebeck W, Lorimier S

Biochem Pharmacol. 2011 Mar 1;81(5):626-35

The NC1 domain of type XIX collagen inhibits melanoma cell migration.

Toubal A, Ramont L, Terryn C, Brassart-Pasco S, Patigny D, Sapi J, Monboisse JC, Maquart FX

Eur J Dermatol. 2010 Nov-Dec;20(6):712-8

Synthesis and biological evaluation of new penta- and heptacyclic indolo- and quinolinocarbazole ring systems obtained via Pd(0) catalysed reductive N-heteroannulation.

Laronze-Cochard M, Cochard F, Daras E, Lansiaux A, Brassart B, Vanquelef E, Prost E, Nuzillard JM, Baldeyrou B, Goosens JF, Lozach O, Meijer L, Riou JF, Henon E, Sapi J

Org Biomol Chem. 2010 Oct 21;8(20):4625-36