Loustau T, Mitrentsi I, Wang N, Spenlé C, Pavlidaki A, Tranchant T, Riegel G, Venu A, Oueidat R, Koch M, Dumas M, Wack F, Hirschler A, Carapito C, Paul N, Carapito R, Mörgelin M, Hansen U, Azzi J, Aubergeon L, Salomé N, Dhaouadi S, Grenot P, Bouhaouala-Zahar B, La Cioppa S, Oertle P, Izzi V, Plodinec M, Noel G, Burckel H, Orend G

EMBO Mol Med. 2026 03 31;:

Human LFA-1 governs T cell immune surveillance of the skin.

Yatim A, Youssefian L, Idani A, Mourelatos H, Alipour Olyaei N, Habibi L, Peel JN, Gaballa M, Kim C, Lee D, Le Floc'h C, Chan YH, Martin-Fernandez M, Pelletier L, Nakajima K, Fayand A, Momenilandi M, Seeleuthner Y, Chaldebas M, Saeidian AH, Mahmoudi H, Nikbakht N, Deswarte C, Kerrouche N, Sahel H, Parvaneh N, Tamizifar B, Sherkat R, Chanal J, Firooz A, Alizadeh Z, Lorenzo-Diaz L, Mariaggi AA, Ogishi M, Diep A, Hammadi B, Kerrouche N, Rinchai D, Sedighzadeh S, Mehrjooy S, Akrami SM, Lenormand C, Radosavljevic M, Rosain J, Zhang SY, Boisson B, Zhang P, Boisson-Dupuis S, Krueger JG, Prétet JL, Waterboer T, Pourpak Z, Fazlollahi MR, Abel L, Bogunovic D, Shahrooei M, Cobat A, Carapito R, Molitor A, Vahidnezhad H, Béziat V, Bahram S, Jouanguy E, Casanova JL

Sci Immunol. 2026 02 27;11(116):eadz8360

Cell viscosity influences haematogenous dissemination and metastatic extravasation of tumour cells.

Gensbittel V, Yesilata Z, Bochler L, Follain G, Nemoz-Billet L, Lefebvre O, Uhlmann K, Larnicol A, Ammirati GEM, Harlepp S, Goswami R, Girardo S, Paulen L, Hyenne V, Mittelheisser V, Stemmelen T, Molitor A, Carapito R, Belthier G, Pannequin J, Kräter M, Müller DJ, Balzani D, Guck J, Osmani N, Goetz JG

Nat Mater. 2026 01 19;:

Novel genotypes, phenotypes, and triggers in humans with OTULIN haploinsufficiency.

van der Linden TJ, Arts RJW, Biggs CM, Habibi L, Batlle-Masó L, van Laarhoven A, Scheepmaker LM, Yousefi P, Gómez-Raccio AC, Alizadeh Z, Mulders-Manders CM, Oever JT, Schuurs-Hoeijmakers J, Alipour-Olyei N, Molitor A, Di Giovanni D, Carapito R, Bahram S, Seminario G, Bezrodnik L, Momenilandi M, Shahrooei M, Bustamante J, Aksentijevich I, Kastner D, Fazlollahi MR, Colobran R, Turvey SE, van de Veerdonk FL, Casanova JL, Boisson B, Bardoel BW, Spaan AN

J Hum Immun. 2025 11 3;1(4):

Lymphopenia drives T cell exhaustion in immunodeficient STING gain-of-function mice.

Freytag D, Giorgiutti S, Hopsomer G, Wadier N, Depauw S, Mertz P, Augé F, Carapito R, Couillin I, Korganow AS, Pala F, Bosticardo M, Notarangelo LD, Rieux-Laucat F, Riteau N, Kirstetter P, Soulas-Sprauel P

EMBO Mol Med. 2025 08 13;:

Complete Complement Factor I (CFI) deficiency: a systematic review of forty-nine patients including three novel cases.

Rajabi E, Kheirabadi MC, Olyaei NA, Molitor A, Khorshidi MSM, Heidari M, Abbasi A, Rostami P, Mahdavi M, Carapito R, Shahrooei M, Bahram S, Parvaneh N

BMC Immunol. 2025 07 26;26(1):54

Nanomaterials Trigger Functional Anti-Tumoral Responses in Primary Human Immune Cells.

Mittelheisser V, Lefebvre O, Banerjee M, Ghosh S, Dupas A, Diringer MC, Blumberger J, Bochler L, Harlepp S, Larnicol A, Pichot A, Stemmelen T, Molitor A, Moritz C, Carapito C, Carapito R, Charbonnière LJ, Lux F, Tillement O, Goetz JG, Detappe A

Adv Sci (Weinh). 2025 07 12;:e05729

Peripheral positioning of lysosomes supports melanoma aggressiveness.

Jerabkova-Roda K, Peralta M, Huang KJ, Mousson A, Bourgeat Maudru C, Bochler L, Busnelli I, Karali R, Justiniano H, Lisii LM, Carl P, Mittelheisser V, Asokan N, Larnicol A, Lefebvre O, Lachuer H, Pichot A, Stemmelen T, Molitor A, Scheid L, Frenger Q, Gros F, Hirschler A, Delalande F, Sick E, Carapito R, Carapito C, Lipsker D, Schauer K, Rondé P, Hyenne V, Goetz JG

Nat Commun. 2025 04 9;16(1):3375

A novel ITGB2 variant in a patient with severe recurrent pyoderma gangrenosum-like lesions and underlying leukocyte adhesion deficiency type I: case report and literature review.

Norouzi-Barough L, Olyaei NA, Carapito R, Molitor A, Biglari S, Poostiyan N, Shahrooei M, Vahidnezhad H, Tabatabaiefar MA, Bahram S, Sherkat R

Arch Dermatol Res. 2025 04 7;317(1):681

Deciphering HIV vaccine-induced Antibody response according to ethnicity.

Lin LY, Ferte T, Chachage M, Casteano C, Laumond G, Schmidt S, Tahar O, Carapito R, Bekker LG, Churchyard G, Keefer M, Moodie Z, Viegas E, Geldmacher C, Lhomme E, Moog C

AIDS. 2025 03 31;:

Clinical Characterization and Mutation Analysis of 13 Iranian Ataxia Telangiectasia Patients: Introducing Two Novel Mutations.

Badalzadeh M, Soleimani Bavani M, Alizadeh Z, Mirmoghtadaei M, Shakerian L, Bahram S, Molitor A, Carapito R, Moradi L, Razaghian A, Assari R, Movahedi M, Shariat M, Houshmand M, Habibi L, Hamidieh AA, Ashrafi MR, Fazlollahi MR, Pourpak Z

Iran J Allergy Asthma Immunol. 2025 03 10;24(2):187-197

Endothelial calcium firing mediates the extravasation of metastatic tumor cells.

Peralta M, Dupas A, Larnicol A, Lefebvre O, Goswami R, Stemmelen T, Molitor A, Carapito R, Girardo S, Osmani N, Goetz JG

iScience. 2025 02 21;28(2):111690

Epidermal maintenance of Langerhans cells relies on autophagy-regulated lipid metabolism.

Arbogast F, Sal-Carro R, Boufenghour W, Frenger Q, Bouis D, Filippi De La Palavesa L, Fauny JD, Griso O, Puccio H, Fima R, Huby T, Gautier EL, Molitor A, Carapito R, Bahram S, Romani N, Clausen BE, Voisin B, Mueller CG, Gros F, Flacher V

J Cell Biol. 2025 02 3;224(2):

Evolution of anti-MICA antibodies after imlifidase infusion for a high immunological risk kidney transplantation.

Beaudrey T, Apithy MJ, Olagne J, Lemonnier L, Perrin P, Vargas GG, Jahn I, Radosavljevic M, Bahram S, Carapito R, Caillard S

Hum Immunol. 2025 01 17;86(2):111213

RICTOR variants are associated with neurodevelopmental disorders.

Carapito R, Molitor A, Pavinato L, Skeyni A, Lambert M, Pichot A, Jiang J, Spinnhirny P, Zimmermann L, Boucher P, Chung CWT, Elserafy N, Blair EM, Li D, Elisabeth B, Kotzaeridou U, Karch S, Wagner M, Lunsing RJ, Pfundt R, Boycott KM, Bruel AL, Mau-Them FT, Moutton S, Conti V, Mei D, Cetica V, Guerrini R, Brunet T, Rump P, Mussa A, Brusco A, Lemire G, de Vries BBA, Miao Z, Isidor B, Bahram S

Eur J Hum Genet. 2024 12 30;:

Machine learning for precision diagnostics of autoimmunity.

Kruta J, Carapito R, Trendelenburg M, Martin T, Rizzi M, Voll RE, Cavalli A, Natali E, Meier P, Stawiski M, Mosbacher J, Mollet A, Santoro A, Capri M, Giampieri E, Schkommodau E, Miho E

Sci Rep. 2024 11 13;14(1):27848

Early diagnosis of immunodeficient patients with partial albinism: The role of hair study and peripheral blood smear.

Tajik S, Fazlollahi MR, Alizadeh Z, Badalzadeh M, Houshmand M, Razaghian A, Bahram S, Molitor A, Carapito R, Shariat M, Hamidieh AA, Behniafard N, Abdolkarimi B, Rostami T, Moin M, Pourpak Z

Pediatr Allergy Immunol. 2024 11;35(11):e14264

Targeting the MAtrix REgulating MOtif abolishes several hallmarks of cancer, triggering antitumor immunity.

Li C, Kaur A, Pavlidaki A, Spenlé C, Rajnpreht I, Donnadieu E, Salomé N, Molitor A, Carapito R, Wack F, Erne W, Lefebvre O, Averous G, Mitrentsi I, Loustau T, Orend G

Proc Natl Acad Sci U S A. 2024 10 15;121(42):e2404485121

A pleiotropic recurrent dominant variant causes a complex multisystemic disease.

Molitor A, Lederle A, Radosavljevic M, Sapuru V, Zavorka Thomas ME, Yang J, Shirin M, Collin-Bund V, Jerabkova-Roda K, Miao Z, Bernard A, Rolli V, Grenot P, Castro CN, Rosenzwajg M, Lewis EG, Person R, Esperón-Moldes US, Kaare M, Nokelainen PT, Batzir NA, Hoffer GZ, Paul N, Stemmelen T, Naegely L, Hanauer A, Bibi-Triki S, Grün S, Jung S, Busnelli I, Tripolszki K, Al-Ali R, Ordonez N, Bauer P, Song E, Zajo K, Partida-Sanchez S, Robledo-Avila F, Kumanovics A, Louzoun Y, Hirschler A, Pichot A, Toker O, Mejía CAM, Parvaneh N, Knapp E, Hersh JH, Kenney H, Delmonte OM, Notarangelo LD, Goetz JG, Kahwash SB, Carapito C, Bajwa RPS, Thomas C, Ehl S, Isidor B, Carapito R, Abraham RS, Hite RK, Marcus N, Bertoli-Avella A, Bahram S

Sci Adv. 2024 09 13;10(37):eado5545

Platelets favor the outgrowth of established metastases.

Garcia-Leon MJ, Liboni C, Mittelheisser V, Bochler L, Follain G, Mouriaux C, Busnelli I, Larnicol A, Colin F, Peralta M, Osmani N, Gensbittel V, Bourdon C, Samaniego R, Pichot A, Paul N, Molitor A, Carapito R, Jandrot-Perrus M, Lefebvre O, Mangin PH, Goetz JG

Nat Commun. 2024 05 13;15(1):3297

Biallelic human SHARPIN loss of function induces autoinflammation and immunodeficiency.

Oda H, Manthiram K, Chavan PP, Rieser E, Veli Ö, Kaya Ö, Rauch C, Nakabo S, Kuehn HS, Swart M, Wang Y, Çelik NI, Molitor A, Ziaee V, Movahedi N, Shahrooei M, Parvaneh N, Alipour-Olyei N, Carapito R, Xu Q, Preite S, Beck DB, Chae JJ, Nehrebecky M, Ombrello AK, Hoffmann P, Romeo T, Deuitch NT, Matthíasardóttir B, Mullikin J, Komarow H, Stoddard J, Niemela J, Dobbs K, Sweeney CL, Anderton H, Lawlor KE, Yoshitomi H, Yang D, Boehm M, Davis J, Mudd P, Randazzo D, Tsai WL, Gadina M, Kaplan MJ, Toguchida J, Mayer CT, Rosenzweig SD, Notarangelo LD, Iwai K, Silke J, Schwartzberg PL, Boisson B, Casanova JL, Bahram S, Rao AP, Peltzer N, Walczak H, Lalaoui N, Aksentijevich I, Kastner DL

Nat Immunol. 2024 04 12;:

An immunogenomic exome landscape of triple positive primary antiphospholipid patients.

Guffroy A, Jacquel L, Seeleuthner Y, Paul N, Poindron V, Maurier F, Delannoy V, Voegeli AC, Zhang P, Nespola B, Molitor A, Apithy MJ, Soulas-Sprauel P, Martin T, Voll RE, Bahram S, Gies V, Casanova JL, Cobat A, Boisson B, Carapito R, Korganow AS

Genes Immun. 2024 01 24;:

[MICA, a novel histocompatibility antigen in kidney transplantation].

Carapito R, Bahram S

Med Sci (Paris). 2024 01;40(1):102-103

Human inherited CCR2 deficiency underlies progressive polycystic lung disease.

Neehus AL, Carey B, Landekic M, Panikulam P, Deutsch G, Ogishi M, Arango-Franco CA, Philippot Q, Modaresi M, Mohammadzadeh I, Corcini Berndt M, Rinchai D, Le Voyer T, Rosain J, Momenilandi M, Martin-Fernandez M, Khan T, Bohlen J, Han JE, Deslys A, Bernard M, Gajardo-Carrasco T, Soudée C, Le Floc'h C, Migaud M, Seeleuthner Y, Jang MS, Nikolouli E, Seyedpour S, Begueret H, Emile JF, Le Guen P, Tavazzi G, Colombo CNJ, Marzani FC, Angelini M, Trespidi F, Ghirardello S, Alipour N, Molitor A, Carapito R, Mazloomrezaei M, Rokni-Zadeh H, Changi-Ashtiani M, Brouzes C, Vargas P, Borghesi A, Lachmann N, Bahram S, Crestani B, Pahari S, Schlesinger LS, Marr N, Bugonovic D, Boisson-Dupuis S, Béziat V, Abel L, Borie R, Young LR, Deterding R, Shahrooei M, Rezaei N, Parvaneh N, Craven D, Gros P, Malo D, Sepulveda FE, Nogee LM, Aladjidi N, Trapnell BC, Casanova JL, Bustamante J

Cell. 2023 12 20;:

Blood flow diverts extracellular vesicles from endothelial degradative compartments to promote angiogenesis.

Mary B, Asokan N, Jerabkova-Roda K, Larnicol A, Busnelli I, Stemmelen T, Pichot A, Molitor A, Carapito R, Lefebvre O, Goetz JG, Hyenne V

EMBO Rep. 2023 11 16;:e57042

C-terminal variants in CDC42 drive type I interferon-dependent autoinflammation in NOCARH syndrome reversible by ruxolitinib.

Kapp FG, Kretschmer S, Beckmann CCA, Wäsch L, Molitor A, Carapito R, Schubert M, Lucas N, Conrad S, Poignant S, Isidor B, Rohlfs M, Kisaarslan AP, Schanze D, Zenker M, Schmitt-Graeff A, Strahm B, Peters A, Yoshimi A, Driever W, Zillinger T, Günther C, Maharana S, Guan K, Klein C, Ehl S, Niemeyer CM, Unal E, Bahram S, Hauck F, Lee-Kirsch MA, Speckmann C

Clin Immunol. 2023 09 21;:109777

Multiomics of three hematological malignancies in a patient reveal their origin from clonal hematopoietic stem cells.

Mayeur S, Molitor A, Miguet L, Rigolot L, Naegely L, Stemmelen T, Meyer S, Toussaint E, Vallat L, Eischen A, Chenard MP, Tavian M, Bahram S, Carapito R, Nicolae A

Blood Cancer J. 2023 08 9;13(1):118

Clinical, immunological and molecular findings of 8 patients with typical and atypical severe combined immunodeficiency: identification of 7 novel mutations by whole exome sequencing.

Alizadeh Z, Fazlollahi MR, Mazinani M, Badalzadeh M, Heydarlou H, Carapito R, Molitor A, de Oteyza ACG, Proietti M, Bavani MS, Shariat M, Fallahpour M, Movahedi M, Moradi L, Grimbacher B, Bahram S, Pourpak Z

Genes Immun. 2023 07 29;:

Clinical and immunological characteristics of 69 leukocyte adhesion deficiency-I patients.

Fazlollahi MR, Hamidieh AA, Moradi L, Shokouhi Shoormati R, Sabetkish N, Esmaeili B, Badalzadeh M, Alizadeh Z, Shamlou S, Movahedi M, Mahloujirad M, Razaghian A, Arshi S, Gharagozlou M, Kalantari A, Bemanian MH, Safari M, Heidarzadeh Arani M, Nabavi M, Parvaneh N, Sadeghi-Shabestari M, Behfar M, Behniafard N, Sherkat R, Ahmadian Heris J, Shariat M, Radmehr R, Houshmand M, Kazemnejad A, Molitor A, Carapito R, Bahram S, Pourpak Z, Moin M

Pediatr Allergy Immunol. 2023 07;34(7):e13990

Measuring the transcriptome-wide effects of aging on murine adipocytes using RNAseq.

De Cauwer A, Pichot A, Molitor A, Stemmelen T, Carapito R, Bahram S, Georgel P

STAR Protoc. 2023 07 1;4(3):102397

Investigating Chemokine-Matrix Networks in Breast Cancer: Tenascin-C Sets the Tone for CCL2.

Gschwandtner M, Gammage AN, Deligne C, Mies LFM, Domaingo A, Murdamoothoo D, Loustau T, Schwenzer A, Derler R, Carapito R, Koch M, Mörgelin M, Orend G, Kungl AJ, Midwood KS

Int J Mol Sci. 2023 05 6;24(9):

Molecular findings and clinical manifestations of 18 Iranian children with Griscelli syndrome type 2: Two novel homozygote mutations in RAB27A gene in a patient.

Tajik S, Badalzadeh M, Houshmand M, Alizadeh Z, Moradi L, Hamidieh AA, Shafiei A, Heris JA, Bahram S, Molitor A, Carapito R, Moin M, Fazlollahi MR, Pourpak Z

Scand J Immunol. 2023 05;97(5):e13264

Genomic profiling of a metastatic anaplastic melanocytic neuroectodermal tumor arising from a mature thymic teratoma as part of a mediastinal germ cell tumor.

Mayeur S, Lhermitte B, Gantzer J, Molitor A, Stemmelen T, Meyer S, Kolmer A, Kurtz JE, Bahram S, Carapito R

Cold Spring Harb Mol Case Stud. 2023 04;9(2):

Rare EIF4A2 variants are associated with a neurodevelopmental disorder characterized by intellectual disability, hypotonia, and epilepsy.

Paul MS, Duncan AR, Genetti CA, Pan H, Jackson A, Grant PE, Shi J, Pinelli M, Brunetti-Pierri N, Garza-Flores A, Shahani D, Saneto RP, Zampino G, Leoni C, Agolini E, Novelli A, Blümlein Tobias B Haack U, Heinritz W, Matzker E, Alhaddad B, Jamra RA, Bartolomaeus T, AlHamdan S, Carapito R, Isidor B, Bahram S, Ritter A, Izumi K, Shakked BP, Barel O, Ben Zeev B, Begtrup A, Carere DA, Mullegama SV, Palculict TB, Calame DG, Schwan K, Aycinena ARP, Traberg R, ,Douzgou S, Pirt H, Ismayilova N, Banka S, Chao HT, Agrawal PB

Am J Hum Genet. 2023 03 2;110(3):548

Human IL-23 is essential for IFN-γ-dependent immunity to mycobacteria.

Philippot Q, Ogishi M, Bohlen J, Puchan J, Arias AA, Nguyen T, Martin-Fernandez M, Conil C, Rinchai D, Momenilandi M, Mahdaviani SA, Keramatipour M, Rosain J, Yang R, Khan T, Neehus AL, Materna M, Han JE, Peel J, Mele F, Weisshaar M, Jovic S, Bastard P, Lévy R, Le Voyer T, Zhang P, Maglorius Renkilaraj MRL, Arango-Franco CA, Pelham S, Seeleuthner Y, Pochon M, Ata MMA, Al Ali F, Migaud M, Soudée C, Kochetkov T, Molitor A, Carapito R, Bahram S, Boisson B, Fieschi C, Mansouri D, Marr N, Okada S, Shahrooei M, Parvaneh N, Chavoshzadeh Z, Cobat A, Bogunovic D, Abel L, Tangye SG, Ma CS, Béziat V, Sallusto F, Boisson-Dupuis S, Bustamante J, Casanova JL, Puel A

Sci Immunol. 2023 02 17;8(80):eabq5204

Infiltrating CD8+ T cells and M2 macrophages are retained in tumor matrix tracks enriched in low tension fibronectin fibers.

Fonta CM, Loustau T, Li C, Surendran SP, Hansen U, Murdamoothoo D, Benn MC, Velazquez-Quesada I, Carapito R, Orend G, Vogel V

Matrix Biol. 2023 01 17;:

Rare EIF4A2 variants are associated with a neurodevelopmental disorder characterized by intellectual disability, hypotonia, and epilepsy.

Paul MS, Duncan AR, Genetti CA, Pan H, Jackson A, Grant PE, Shi J, Pinelli M, Brunetti-Pierri N, Garza-Flores A, Shahani D, Saneto RP, Zampino G, Leoni C, Agolini E, Novelli A, Blümlein U, Haack TB, Heinritz W, Matzker E, Alhaddad B, Abou Jamra R, Bartolomaeus T, AlHamdan S, Carapito R, Isidor B, Bahram S, Ritter A, Izumi K, Shakked BP, Barel O, Ben Zeev B, Begtrup A, Carere DA, Mullegama SV, Palculict TB, Calame DG, Schwan K, Aycinena ARP, Traberg R, ,Douzgou S, Pirt H, Ismayilova N, Banka S, Chao HT, Agrawal PB

Am J Hum Genet. 2022 12 15;:

Dicer1 deficient mice exhibit premature aging and metabolic perturbations in adipocytes.

De Cauwer A, Loustau T, Erne W, Pichot A, Molitor A, Stemmelen T, Carapito R, Orend G, Bahram S, Georgel P

iScience. 2022 10 21;25(10):105149

Advances in Research on COVID-19 Vaccination for People Living with HIV.

Jin J, Wang X, Carapito R, Moog C, Su B

Infect Dis Immun. 2022 10;2(4):213-218

Fc receptors and the diversity of antibody responses to HIV infection and vaccination.

Lin LY, Carapito R, Su B, Moog C

Genes Immun. 2022 06 10;:

A gain-of-function variant in the Wiskott-Aldrich syndrome gene is associated with a MYH9-related disease-like syndrome.

Marx D, Dupuis A, Eckly AE, Molitor A, Olagne J, Touchard G, Kaaki S, Ory C, Faller AL, Gérard B, Cotter M, Westerberg L, Keszei M, Moulin B, Gachet C, Caillard S, Bahram S, Carapito R

Blood Adv. 2022 Apr 11;:

The MHC class I MICA gene is a histocompatibility antigen in kidney transplantation.

Carapito R, Aouadi I, Verniquet M, Untrau M, Pichot A, Beaudrey T, Bassand X, Meyer S, Faucher L, Posson J, Morlon A, Kotova I, Delbos F, Walencik A, Aarnink A, Kennel A, Suberbielle C, Taupin JL, Matern BM, Spierings E, Congy-Jolivet N, Essaydi A, Perrin P, Blancher A, Charron D, Cereb N, Maumy-Bertrand M, Bertrand F, Garrigue V, Pernin V, Weekers L, Naesens M, Kamar N, Legendre C, Glotz D, Caillard S, Ladrière M, Giral M, Anglicheau D, Süsal C, Bahram S

Nat Med. 2022 Mar 14;:

CD4 T cell-intrinsic STING signaling controls the differentiation and effector functions of T1 and T9 cells.

Benoit-Lizon I, Jacquin E, Rivera Vargas T, Richard C, Roussey A, Dal Zuffo L, Martin T, Melis A, Vinokurova D, Shahoei SH, Baeza Garcia A, Pignol C, Giorgiutti S, Carapito R, Boidot R, Végran F, Flavell RA, Ryffel B, Nelson ER, Soulas-Sprauel P, Lawrence T, Apetoh L

J Immunother Cancer. 2022 01;10(1):

A Homozygous Missense Variant in PPP1R1B/DARPP-32 Is Associated With Generalized Complex Dystonia.

Khan A, Molitor A, Mayeur S, Zhang G, Rinaldi B, Lannes B, Lhermitte B, Umair M, Arold ST, Friant S, Rastegar S, Anheim M, Bahram S, Carapito R

Mov Disord. 2021 Nov 24;:

Identification of driver genes for critical forms of COVID-19 in a deeply phenotyped young patient cohort.

Carapito R, Li R, Helms J, Carapito C, Gujja S, Rolli V, Guimaraes R, Malagon-Lopez J, Spinnhirny P, Lederle A, Mohseninia R, Hirschler A, Muller L, Bastard P, Gervais A, Zhang Q, Danion F, Ruch Y, Schenck M, Collange O, Chamaraux-Tran TN, Molitor A, Pichot A, Bernard A, Tahar O, Bibi-Triki S, Wu H, Paul N, Mayeur S, Larnicol A, Laumond G, Frappier J, Schmidt S, Hanauer A, Macquin C, Stemmelen T, Simons M, Mariette X, Hermine O, Fafi-Kremer S, Goichot B, Drenou B, Kuteifan K, Pottecher J, Mertes PM, Kailasan S, Aman MJ, Pin E, Nilsson P, Thomas A, Viari A, Sanlaville D, Schneider F, Sibilia J, Tharaux PL, Casanova JL, Hansmann Y, Lidar D, Radosavljevic M, Gulcher JR, Meziani F, Moog C, Chittenden TW, Bahram S

Sci Transl Med. 2021 Oct 26;:eabj7521

Contrasting role of in autoinflammation: evidence from a case report and mouse models.

Lévy D, Mariotte A, DeCauwer A, Macquin C, Pichot A, Molitor A, Maurier F, Meyer A, Carapito R, Georgel P

RMD Open. 2021 Oct;7(3):

Refining "Long-COVID" by a Prospective Multimodal Evaluation of Patients with Long-Term Symptoms Attributed to SARS-CoV-2 Infection.

Scherlinger M, Felten R, Gallais F, Nazon C, Chatelus E, Pijnenburg L, Mengin A, Gras A, Vidailhet P, Arnould-Michel R, Bibi-Triki S, Carapito R, Trouillet-Assant S, Perret M, Belot A, Bahram S, Arnaud L, Gottenberg JE, Fafi-Kremer S, Sibilia J

Infect Dis Ther. 2021 Jul 10;:

Impairing flow-mediated endothelial remodeling reduces extravasation of tumor cells.

Follain G, Osmani N, Gensbittel V, Asokan N, Larnicol A, Mercier L, Garcia-Leon MJ, Busnelli I, Pichot A, Paul N, Carapito R, Bahram S, Lefebvre O, Goetz JG

Sci Rep. 2021 Jun 23;11(1):13144

Tenascin-C immobilizes infiltrating T lymphocytes through CXCL12 promoting breast cancer progression.

Murdamoothoo D, Sun Z, Yilmaz A, Riegel G, Abou-Faycal C, Deligne C, Velazquez-Quesada I, Erne W, Nascimento M, Mörgelin M, Cremel G, Paul N, Carapito R, Veber R, Dumortier H, Yuan J, Midwood KS, Loustau T, Orend G

EMBO Mol Med. 2021 May 14;:e13270

Temporal multiomic modeling reveals a B-cell receptor proliferative program in chronic lymphocytic leukemia.

Schleiss C, Carapito R, Fornecker LM, Muller L, Paul N, Tahar O, Pichot A, Tavian M, Nicolae A, Miguet L, Mauvieux L, Herbrecht R, Cianferani S, Freund JN, Carapito C, Maumy-Bertrand M, Bahram S, Bertrand F, Vallat L

Leukemia. 2021 Apr 8;:

Atypical focal segmental glomerulosclerosis associated with a new PODXL nonsense variant.

Marx D, Caillard S, Olagne J, Moulin B, Hannedouche T, Touchard G, Dupuis A, Gachet C, Molitor A, Bahram S, Carapito R

Mol Genet Genomic Med. 2021 Mar 29;:e1658

NKG2D ligands in inflammatory joint diseases: analysis in human samples and mouse models.

Mariotte A, Bernardi L, Macquin C, DeCauwer A, Kotova I, Blüml S, Noël D, Scanu A, Punzi L, Carapito R, Sibilia J, Bahram S, Georgel P

Clin Exp Rheumatol. 2021 Jan 8;:

Ral GTPases promote breast cancer metastasis by controlling biogenesis and organ targeting of exosomes.

Ghoroghi S, Mary B, Larnicol A, Asokan N, Klein A, Osmani N, Busnelli I, Delalande F, Paul N, Halary S, Gros F, Fouillen L, Haeberle AM, Royer C, Spiegelhalter C, André-Grégoire G, Mittelheisser V, Detappe A, Murphy K, Timpson P, Carapito R, Blot-Chabaud M, Gavard J, Carapito C, Vitale N, Lefebvre O, Goetz JG, Hyenne V

Elife. 2021 Jan 6;10:

Case Report: Acquired Disseminated BCG in the Context of a Delayed Immune Reconstitution After Hematological Malignancy.

Gies V, Dieudonné Y, Morel F, Sougakoff W, Carapito R, Martin A, Weingertner N, Jacquel L, Hubele F, Kuhnert C, Jung S, Schramm F, Boyer P, Hansmann Y, Danion F, Korganow AS, Guffroy A

Front Immunol. 2021 ;12:696268

Impact of Tenascin-C on Radiotherapy in a Novel Syngeneic Oral Squamous Cell Carcinoma Model With Spontaneous Dissemination to the Lymph Nodes.

Spenlé C, Loustau T, Burckel H, Riegel G, Abou Faycal C, Li C, Yilmaz A, Petti L, Steinbach F, Ahowesso C, Jost C, Paul N, Carapito R, Noël G, Anjuère F, Salomé N, Orend G

Front Immunol. 2021 ;12:636108

NCKAP1L defects lead to a novel syndrome combining immunodeficiency, lymphoproliferation, and hyperinflammation.

Castro CN, Rosenzwajg M, Carapito R, Shahrooei M, Konantz M, Khan A, Miao Z, Groß M, Tranchant T, Radosavljevic M, Paul N, Stemmelen T, Pitoiset F, Hirschler A, Nespola B, Molitor A, Rolli V, Pichot A, Faletti LE, Rinaldi B, Friant S, Mednikov M, Karauzum H, Aman MJ, Carapito C, Lengerke C, Ziaee V, Eyaid W, Ehl S, Alroqi F, Parvaneh N, Bahram S

J. Exp. Med.. 2020 Dec 7;217(12):

SRP54 mutations induce Congenital Neutropenia via dominant-negative effects on XBP1 splicing.

Schürch C, Schaefer T, Müller JS, Hanns P, Arnone M, Dumlin A, Schärer J, Sinning I, Wild K, Skokowa J, Welte K, Carapito R, Bahram S, Konantz M, Lengerke C

Blood. 2020 Nov 23;:

Structural and Functional Impact of SRP54 Mutations Causing Severe Congenital Neutropenia.

Juaire KD, Lapouge K, Becker MMM, Kotova I, Michelhans M, Carapito R, Wild K, Bahram S, Sinning I

Structure. 2020 Oct 13;:

SelectBoost: a general algorithm to enhance the performance of variable selection methods.

Bertrand F, Aouadi I, Jung N, Carapito R, Vallat L, Bahram S, Maumy-Bertrand M

Bioinformatics. 2020 Oct 5;:

A de novo synonymous variant in EFTUD2 disrupts normal splicing and causes mandibulofacial dysostosis with microcephaly: case report.

Jacob A, Pasquier J, Carapito R, Auradé F, Molitor A, Froguel P, Fakhro K, Halabi N, Viot G, Bahram S, Rafii A

BMC Med. Genet.. 2020 Sep 17;21(1):182

Progressive multifocal leukoencephalopathy and sarcoidosis under interleukin 7: The price of healing.

Guffroy A, Solis M, Gies V, Dieudonne Y, Kuhnert C, Lenormand C, Kremer L, Molitor A, Carapito R, Hansmann Y, Poindron V, Martin T, Hirschi S, Korganow AS

Neurol Neuroimmunol Neuroinflamm. 2020 Sep;7(5):

Two Cases of Recessive Intellectual Disability Caused by and Variants.

Khan A, Miao Z, Umair M, Ullah A, Alshabeeb MA, Bilal M, Ahmad F, Rappold GA, Ansar M, Carapito R

Genes (Basel). 2020 Aug 31;11(9):

Improvement of therapy-induced myelodysplastic syndrome by infusion of autologous CD34-positive hematopoietic progenitor cells without chemotherapy.

Alary AS, Vignon M, Carapito R, Halabi N, Willems L, Green A, Chapuis N, Heshmati F, Cuccuini W, Kaltenbach S, Radford-Weiss I, Kosmider O, Bouscary D, Bahram S, Rafii A, Tamburini J

Leuk. Lymphoma. 2020 Aug 28;:1-4

A FcɣRIIa polymorphism has a HLA-B57 and HLA-B27 independent effect on HIV disease outcome.

Carapito R, Mayr L, Molitor A, Verniquet M, Schmidt S, Tahar O, Partisani M, Rey D, Lambotte O, Bahram S, Moog C

Genes Immun.. 2020 Aug 5;:

Tenascin-C orchestrates an immune suppressive tumor microenvironment in oral squamous cell carcinoma.

Spenlé C, Loustau T, Murdamoothoo D, Erne W, Beghelli-de la Forest Divonne S, Veber R, Petti L, Bourdely P, Mörgelin M, Brauchle EM, Crémel G, Randrianarisoa V, Camara A, Rekima S, Schaub S, Nouhen K, Imhof T, Hansen U, Paul N, Carapito R, Pythoud N, Hirschler A, Carapito C, Dumortier H, Mueller CG, Koch M, Schenke-Layland K, Kon S, Sudaka A, Anjuere F, Van Obberghen-Schilling E, Orend G

Cancer Immunol Res. 2020 Jul 14;:

Compatibility at amino acid position 98 of MICB reduces the incidence of graft-versus-host disease in conjunction with the CMV status.

Carapito R, Aouadi I, Pichot A, Spinnhirny P, Morlon A, Kotova I, Macquin C, Rolli V, Cesbron A, Gagne K, Oudshoorn M, van der Holt B, Labalette M, Spierings E, Picard C, Loiseau P, Tamouza R, Toubert A, Parissiadis A, Dubois V, Paillard C, Maumy-Bertrand M, Bertrand F, von dem Borne PA, Kuball JHE, Michallet M, Lioure B, Peffault de Latour R, Blaise D, Cornelissen JJ, Yakoub-Agha I, Claas F, Moreau P, Charron D, Mohty M, Morishima Y, Socié G, Bahram S

Bone Marrow Transplant.. 2020 Apr 14;:

Protocol for TRAUMADORNASE: a prospective, randomized, multicentre, double-blinded, placebo-controlled clinical trial of aerosolized dornase alfa to reduce the incidence of moderate-to-severe hypoxaemia in ventilated trauma patients.

Pottecher J, Noll E, Borel M, Audibert G, Gette S, Meyer C, Gaertner E, Legros V, Carapito R, Uring-Lambert B, Sauleau E, Land WG, Bahram S, Meyer A, Geny B, Diemunsch P

Trials. 2020 Mar 18;21(1):274

Matrix-targeting immunotherapy controls tumor growth and spread by switching macrophage phenotype.

Deligne C, Murdamoothoo D, Gammage AN, Gschwandtner M, Erne W, Loustau T, Marzeda AM, Carapito R, Paul N, Velázquez-Quesada I, Mazzier I, Sun Z, Orend G, Midwood KS

Cancer Immunol Res. 2020 Jan 15;:

A mouse model of MSU-induced acute inflammation suggests imiquimod-dependent targeting of as relevant therapy for gout patients.

Mariotte A, De Cauwer A, Po C, Abou-Faycal C, Pichot A, Paul N, Aouadi I, Carapito R, Frisch B, Macquin C, Chatelus E, Sibilia J, Armspach JP, Bahram S, Georgel P

Theranostics. 2020 ;10(5):2158-2171

High-Throughput Genotyping of Over Two Million Samples: Workflow and Allele Frequencies.

Klussmeier A, Massalski C, Putke K, Schäfer G, Sauter J, Schefzyk D, Pruschke J, Hofmann J, Fürst D, Carapito R, Bahram S, Schmidt AH, Lange V

Front Immunol. 2020 ;11:314

Exome sequencing identifies a novel missense variant in CTSC causing nonsyndromic aggressive periodontitis.

Molitor A, Prud'homme T, Miao Z, Conrad S, Bloch-Zupan A, Pichot A, Hanauer A, Isidor B, Bahram S, Carapito R

J. Hum. Genet.. 2019 May 8;:

HLA*LA - HLA typing from linearly projected graph alignments.

Dilthey AT, Mentzer AJ, Carapito R, Cutland C, Cereb N, Madhi SA, Rhie A, Koren S, Bahram S, McVean G, Phillippy AM

Bioinformatics. 2019 Apr 3;:

Multi-omics dataset to decipher the complexity of drug resistance in diffuse large B-cell lymphoma.

Fornecker LM, Muller L, Bertrand F, Paul N, Pichot A, Herbrecht R, Chenard MP, Mauvieux L, Vallat L, Bahram S, Cianférani S, Carapito R, Carapito C

Sci Rep. 2019 Jan 29;9(1):895

Update on Fc-Mediated Antibody Functions Against HIV-1 Beyond Neutralization.

Su B, Dispinseri S, Iannone V, Zhang T, Wu H, Carapito R, Bahram S, Scarlatti G, Moog C

Front Immunol. 2019 ;10:2968

ZMIZ1 Variants Cause a Syndromic Neurodevelopmental Disorder.

Carapito R, Ivanova EL, Morlon A, Meng L, Molitor A, Erdmann E, Kieffer B, Pichot A, Naegely L, Kolmer A, Paul N, Hanauer A, Tran Mau-Them F, Jean-Marçais N, Hiatt SM, Cooper GM, Tvrdik T, Muir AM, Dimartino C, Chopra M, Amiel J, Gordon CT, Dutreux F, Garde A, Thauvin-Robinet C, Wang X, Leduc MS, Phillips M, Crawford HP, Kukolich MK, Hunt D, Harrison V, Kharbanda M, ,,Smigiel R, Gold N, Hung CY, Viskochil DH, Dugan SL, Bayrak-Toydemir P, Joly-Helas G, Guerrot AM, Schluth-Bolard C, Rio M, Wentzensen IM, McWalter K, Schnur RE, Lewis AM, Lalani SR, Mensah-Bonsu N, Céraline J, Sun Z, Ploski R, Bacino CA, Mefford HC, Faivre L, Bodamer O, Chelly J, Isidor B, Bahram S

Am. J. Hum. Genet.. 2018 Dec 26;:

An unusually high substitution rate in transplant-associated BK polyomavirus in vivo is further concentrated in HLA-C-bound viral peptides.

Domingo-Calap P, Schubert B, Joly M, Solis M, Untrau M, Carapito R, Georgel P, Caillard S, Fafi-Kremer S, Paul N, Kohlbacher O, González-Candelas F, Bahram S

PLoS Pathog.. 2018 Oct 18;14(10):e1007368

Multi-OMICS analyses unveil as a potential modifier gene in mevalonate kinase deficiency.

Carapito R, Carapito C, Morlon A, Paul N, Vaca Jacome AS, Alsaleh G, Rolli V, Tahar O, Aouadi I, Rompais M, Delalande F, Pichot A, Georgel P, Messer L, Sibilia J, Cianferani S, Van Dorsselaer A, Bahram S

Ann. Rheum. Dis.. 2018 Jul 20;:

Hemodynamic Forces Tune the Arrest, Adhesion, and Extravasation of Circulating Tumor Cells.

Follain G, Osmani N, Azevedo AS, Allio G, Mercier L, Karreman MA, Solecki G, Garcia Leòn MJ, Lefebvre O, Fekonja N, Hille C, Chabannes V, Dollé G, Metivet T, Hovsepian F, Prudhomme C, Pichot A, Paul N, Carapito R, Bahram S, Ruthensteiner B, Kemmling A, Siemonsen S, Schneider T, Fiehler J, Glatzel M, Winkler F, Schwab Y, Pantel K, Harlepp S, Goetz JG

Dev. Cell. 2018 Apr 9;45(1):33-52.e12

Mutations in signal recognition particle SRP54 cause syndromic neutropenia with Shwachman-Diamond-like features.

Carapito R, Konantz M, Paillard C, Miao Z, Pichot A, Leduc MS, Yang Y, Bergstrom KL, Mahoney DH, Shardy DL, Alsaleh G, Naegely L, Kolmer A, Paul N, Hanauer A, Rolli V, Müller JS, Alghisi E, Sauteur L, Macquin C, Morlon A, Sancho CS, Amati-Bonneau P, Procaccio V, Mosca-Boidron AL, Marle N, Osmani N, Lefebvre O, Goetz JG, Unal S, Akarsu NA, Radosavljevic M, Chenard MP, Rialland F, Grain A, Béné MC, Eveillard M, Vincent M, Guy J, Faivre L, Thauvin-Robinet C, Thevenon J, Myers K, Fleming MD, Shimamura A, Bottollier-Lemallaz E, Westhof E, Lengerke C, Isidor B, Bahram S

J. Clin. Invest.. 2017 Oct;:

MicroRNA-146a governs fibroblast activation and joint pathology in arthritis.

Saferding V, Puchner A, Goncalves-Alves E, Hofmann M, Bonelli M, Brunner JS, Sahin E, Niederreiter B, Hayer S, Kiener HP, Einwallner E, Nehmar R, Carapito R, Georgel P, Koenders MI, Boldin M, Schabbauer G, Kurowska-Stolarska M, Steiner G, Smolen JS, Redlich K, Blüml S

J. Autoimmun.. 2017 Aug;82:74-84

A new MHC-linked susceptibility locus for primary Sjögren's syndrome: MICA.

Carapito R, Gottenberg JE, Kotova I, Untrau M, Michel S, Naegely L, Aouadi I, Kwemou M, Paul N, Pichot A, Locke J, Bowman SJ, Griffiths B, Sivils KL, Sibilia J, Inoko H, Micelli-Richard C, Nocturne G, Ota M, Ng WF, Mariette X, Bahram S

Hum. Mol. Genet.. 2017 Apr;:

Natural Killer Group 2, Member D/NKG2D Ligands in Hematopoietic Cell Transplantation.

Carapito R, Aouadi I, Ilias W, Bahram S

Front Immunol. 2017 ;8:368

Protein-altering MYH3 variants are associated with a spectrum of phenotypes extending to spondylocarpotarsal synostosis syndrome.

Carapito R, Goldenberg A, Paul N, Pichot A, David A, Hamel A, Dumant-Forest C, Leroux J, Ory B, Isidor B, Bahram S

Eur. J. Hum. Genet.. 2016 Dec;24(12):1746-1751

Next-Generation Sequencing of the HLA locus: Methods and impacts on HLA typing, population genetics and disease association studies.

Carapito R, Radosavljevic M, Bahram S

Hum. Immunol.. 2016 Nov;77(11):1016-1023

The TRANSPLANTEX initiative.

Bahram S, Carapito R, Gourraud PA, Charron D

Hum. Immunol.. 2016 Nov;77(11):1005-1007

Matching for the nonconventional MHC-I MICA gene significantly reduces the incidence of acute and chronic GVHD.

Carapito R, Jung N, Kwemou M, Untrau M, Michel S, Pichot A, Giacometti G, Macquin C, Ilias W, Morlon A, Kotova I, Apostolova P, Schmitt-Graeff A, Cesbron A, Gagne K, Oudshoorn M, van der Holt B, Labalette M, Spierings E, Picard C, Loiseau P, Tamouza R, Toubert A, Parissiadis A, Dubois V, Lafarge X, Maumy-Bertrand M, Bertrand F, Vago L, Ciceri F, Paillard C, Querol S, Sierra J, Fleischhauer K, Nagler A, Labopin M, Inoko H, von dem Borne PA, Kuball J, Ota M, Katsuyama Y, Michallet M, Lioure B, Peffault de Latour R, Blaise D, Cornelissen JJ, Yakoub-Agha I, Claas F, Moreau P, Milpied N, Charron D, Mohty M, Zeiser R, Socié G, Bahram S

Blood. 2016 Oct;128(15):1979-1986

Homozygosity for the V377I mutation in mevalonate kinase causes distinct clinical phenotypes in two sibs with hyperimmunoglobulinaemia D and periodic fever syndrome (HIDS).

Messer L, Alsaleh G, Georgel P, Carapito R, Waterham HR, Dali-Youcef N, Bahram S, Sibilia J

RMD Open. 2016 ;2(1):e000196

Germline variation of TNFAIP3 in primary Sjogren's syndrome-associated lymphoma.

Nocturne G, Tarn J, Boudaoud S, Locke J, Miceli-Richard C, Hachulla E, Dubost JJ, Bowman S, Gottenberg JE, Criswell LA, Lessard CJ, Sivils KL, Carapito R, Bahram S, Seror R, Ng WF, Mariette X

Ann Rheum Dis. 2015 Sep 2. pii: annrheumdis-2015-207731