COVID-19 promotes endothelial dysfunction and thrombogenicity: Role of pro-inflammatory cytokines/SGLT2 pro-oxidant pathway.
Fiche publication
Date publication
octobre 2023
Journal
Journal of thrombosis and haemostasis : JTH
Auteurs
Membres identifiés du Cancéropôle Est :
Pr LESSINGER Jean-Marc, Pr MEYER Nicolas, Pr SCHINI-KERTH Valérie, Dr AUGER Cyril
Tous les auteurs :
Mroueh A, Fakih W, Carmona A, Trimaille A, Matsushita K, Marchandot B, Qureshi AW, Gong DS, Auger C, Sattler L, Reydel A, Hess S, Oulehri W, Vollmer O, Lessinger JM, Meyer N, Pieper MP, Jesel L, Bäck M, Schini-Kerth V, Morel O
Lien Pubmed
Résumé
COVID-19 is associated with increased risk of cardiovascular complications. Although cytokines have a predominant role in endothelium damage, the precise molecular mechanisms are far from being elucidated.
Mots clés
COVID-19, SGLT2, endothelium, inflammation, thrombosis
Référence
J Thromb Haemost. 2023 10 3;: