Transfusion of fresh washed platelets does not prevent experimental polymicrobial-induced septic shock in mice.
Fiche publication
Date publication
novembre 2021
Journal
Journal of thrombosis and haemostasis : JTH
Auteurs
Membres identifiés du Cancéropôle Est :
Dr GACHET Christian
Tous les auteurs :
Rabouël Y, Magnenat S, Lefebvre F, Delabranche X, Gachet C, Hechler B
Lien Pubmed
Résumé
The specific role of platelets during sepsis is not yet fully understood, probably related to the paradox of platelets being potentially beneficial but also deleterious via their thrombotic functions.
Mots clés
antiplatelet drug, mouse model, platelet transfusion, sepsis, septic shock, thrombocytopenia
Référence
J Thromb Haemost. 2021 Nov 9;: