Instrumental analysis of RNA modifications.
Fiche publication
Date publication
février 2021
Journal
Critical reviews in biochemistry and molecular biology
Auteurs
Membres identifiés du Cancéropôle Est :
Dr MARCHAND Virginie
Tous les auteurs :
Yoluç Y, Ammann G, Barraud P, Jora M, Limbach PA, Motorin Y, Marchand V, Tisné C, Borland K, Kellner S
Lien Pubmed
Résumé
Organisms from all domains of life invest a substantial amount of energy for the introduction of RNA modifications into nearly all transcripts studied to date. Instrumental analysis of RNA can focus on the modified residues and reveal the function of these epitranscriptomic marks. Here, we will review recent advances and breakthroughs achieved by NMR spectroscopy, sequencing, and mass spectrometry of the epitranscriptome.
Mots clés
E, pitranscriptome
Référence
Crit Rev Biochem Mol Biol. 2021 Feb 22;:1-27