Ticagrelor Prevents Endothelial Cell Apoptosis through the Adenosine Signalling Pathway in the Early Stages of Hypoxia.
Fiche publication
Date publication
mai 2020
Journal
Biomolecules
Auteurs
Membres identifiés du Cancéropôle Est :
Dr BRASSART-PASCO Sylvie, Pr NGUYEN Philippe
Tous les auteurs :
Feliu C, Peyret H, Brassart-Pasco S, Oszust F, Poitevin G, Nguyen P, Millart H, Djerada Z
Lien Pubmed
Résumé
Several studies have reported the beneficial effects of anti-platelet drugs in cardioprotection against ischaemia-reperfusion injuries. To date, no studies have focused on the indirect cytoprotective effects of ticagrelor via adenosine receptor on the endothelium.
Mots clés
adenosine receptors, cytoprotective effect, endothelium, extracellular adenosine, ticagrelor
Référence
Biomolecules. 2020 May 9;10(5):