Role of the NO/cGMP pathway and renin-angiotensin system in the hypotensive and diuretic effects of aqueous soluble fraction from Crataegus songarica K. Koch.

Fiche publication


Date publication

novembre 2019

Journal

Journal of ethnopharmacology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr SCHINI-KERTH Valérie


Tous les auteurs :
Younis W, Alamgeer, Schini-Kerth VB, Brentan da Silva D, Junior AG, Bukhari IA, Assiri AM

Résumé

Fruits of Crataegus songarica K. Koch. (Rosaceae) are commonly used in folk medicine for their diuretic properties to treat hypertension and congestive heart failure. To date, no scientific data has been published to support the diuretic potential.

Mots clés

ACE inhibition, Acetazolamide (PubChem CID: 1986), Atropine (PubChem CID: 174174), Captopril (PubChem CID: 44093), Crataegus songarica, Dicloromethane (PubChem CID: 6344), Diuretic, Ethyl acetate (PubChem CID: 8857), Flavonoids, Hexamethonium bromide (PubChem CID: 5938), Hydrochlorothiazide (PubChem CID: 3639), Hypertension, Indomethacin (PubChem CID: 3715), Methanol (PubChem CID: 887), N-ω- Nitro-L-arginine methyl ester (PubChem CID: 39836), NO/cGMP pathway, Ouabain octahydrate (PubChem CID: 6364534), Propranolol (PubChem CID: 4946), n-Butanol (PubChem CID: 263), n-Hexane (PubChem CID: 8058)

Référence

J Ethnopharmacol. 2019 Nov 15;: