Decreased expression of GPC1 in human skin keratinocytes and epidermis during ageing.
Fiche publication
Date publication
août 2019
Journal
Experimental gerontology
Auteurs
Membres identifiés du Cancéropôle Est :
Dr BREZILLON Stéphane, Dr GARBAR Christian, Pr RAMONT Laurent
Tous les auteurs :
Perrot G, Colin-Pierre C, Ramont L, Proult I, Garbar C, Bardey V, Jeanmaire C, Mine S, Danoux L, Berthélémy N, Maquart FX, Wegrowski Y, Brézillon S
Lien Pubmed
Résumé
Glypicans (GPCs) are heparan sulfate cell membrane proteoglycans containing glycosylphosphatidylinositol (GPI) anchor. They play important role in cell behavior by activating/presenting numerous growth factors and cytokines.
Mots clés
Ageing, Epidermis, Glypican 1, Human skin, Keratinocytes
Référence
Exp. Gerontol.. 2019 Aug 17;:110693