Complementary Role of P2 and Adenosine Receptors in ATP Induced-Anti-Apoptotic Effects Against Hypoxic Injury of HUVECs.

Fiche publication


Date publication

mars 2019

Journal

International journal of molecular sciences

Auteurs

Membres identifiés du Cancéropôle Est :
Pr NGUYEN Philippe


Tous les auteurs :
Feliu C, Peyret H, Poitevin G, Cazaubon Y, Oszust F, Nguyen P, Millart H, Djerada Z

Résumé

Vascular endothelial injury during ischemia generates apoptotic cell death and precedes apoptosis of underlying tissues. We aimed at studying the role of extracellular adenosine triphosphate (ATP) on endothelial cells protection against hypoxia injury.

Mots clés

ATP, adenosine, endothelial cells, hypoxic stress, purinergic signaling

Référence

Int J Mol Sci. 2019 Mar 22;20(6):