Cell therapy in critical limb ischemia: A comprehensive analysis of two cell therapy products.
Fiche publication
Date publication
février 2017
Journal
Cytotherapy
Auteurs
Membres identifiés du Cancéropôle Est :
Pr NGUYEN Philippe
Tous les auteurs :
Tournois C, Pignon B, Sevestre MA, Al-Rifai R, Creuza V, Poitevin G, François C, Nguyen P
Lien Pubmed
Résumé
Cell therapy has been proposed as a salvage limb procedure in critical limb ischemia (CLI). In spite of the fact that clinical trials found some efficacy, the mechanism of action remains elusive. The objective of this study was to characterize two autologous cell therapy products (CTPs) obtained from patients with advanced peripheral arterial disease.
Mots clés
angiogenesis, cell therapy, critical limb ischemia, endothelial progenitor cells, mesenchymal stem cells, transcriptome
Référence
Cytotherapy. 2017 Feb;19(2):299-310