Serotonergic 5-HT2B receptors in mitral valvulopathy: bone marrow mobilization of endothelial progenitors.
Fiche publication
Date publication
août 2017
Journal
British journal of pharmacology
Auteurs
Membres identifiés du Cancéropôle Est :
Mme EBEL Claudine, Dr GACHET Christian
Tous les auteurs :
Ayme-Dietrich E, Lawson R, Côté F, de Tapia C, Da Silva S, Ebel C, Hechler B, Gachet C, Guyonnet J, Rouillard H, Stoltz J, Quentin E, Banas S, Daubeuf F, Frossard N, Gasser B, Mazzucotelli JP, Hermine O, Maroteaux L, Monassier L
Lien Pubmed
Résumé
Valvular heart disease is highly prevalent in industrialized countries. Chronic use of anorexigens, amphetamine or ergot derivatives targeting the serotonin system has been associated with valvular heart disease.
Mots clés
Animals, Bone Marrow Transplantation, Endothelial Progenitor Cells, metabolism, Heart Valve Diseases, metabolism, Male, Mice, Transgenic, Mitral Valve, drug effects, Norfenfluramine, pharmacology, Receptor, Serotonin, 5-HT2A, genetics, Receptor, Serotonin, 5-HT2B, genetics, Serotonin 5-HT2 Receptor Antagonists, pharmacology
Référence
Br. J. Pharmacol.. 2017 Aug;: