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IL-10 secretion by CD8 T cells orchestrates early NK cell recruitment and antitumor immunity after anti-VEGFR-2/PD-1 therapy.

Geindreau M, Pignol C, Coënon L, Varin A, Racoeur C, Milian L, Roger N, Chalmin F, Vernet T, Alibert L, Bellaye PS, Thibaudin M, Louis C, Wicks I, Truntzer C, Boidot R, Paul C, Lamarthée B, Vegran F, Ghiringhelli F, Bruchard M

J Immunother Cancer. 2026 06 22;14(6):

Stearoyl-CoA desaturase-1 controls the differentiation and antitumoral function of Th9 lymphocytes.

Groetz E, Perrey S, Baeza Garcia A, Dumont A, Pichon L, Kieu CTLV, Pierre L, Thomas C, Flavell R, Limagne E, Vegran F, Apetoh L, Ghiringhelli F, Rialland M

J Immunother Cancer. 2026 01 16;14(1):

The intrinsic expression of NLRP3 in Th17 cells promotes their protumor activity and conversion into Tregs.

Accogli T, Hibos C, Milian L, Geindreau M, Richard C, Humblin E, Mary R, Chevrier S, Jacquin E, Bernard A, Chalmin F, Paul C, Ryffel B, Apetoh L, Boidot R, Bruchard M, Ghiringhelli F, Vegran F

Cell Mol Immunol. 2025 04 7;:

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