Fiche publication


Date publication

juin 2026

Journal

Journal for immunotherapy of cancer

Auteurs

Membres identifiés du Cancéropôle Est :
Dr BOIDOT Romain , Pr GHIRINGHELLI François , Pr PAUL Catherine , Mme TRUNTZER Caroline , Dr VEGRAN Frédérique , Dr BRUCHARD Mélanie , Dr CHALMIN Fanny , Dr BELLAYE Pierre-Simon , Dr THIBAUDIN Marion


Tous les auteurs :
Geindreau M, Pignol C, Coënon L, Varin A, Racoeur C, Milian L, Roger N, Chalmin F, Vernet T, Alibert L, Bellaye PS, Thibaudin M, Louis C, Wicks I, Truntzer C, Boidot R, Paul C, Lamarthée B, Vegran F, Ghiringhelli F, Bruchard M

Résumé

The combination of antiangiogenic therapy with immune checkpoint blockade has demonstrated significant clinical benefits in various cancers, however, the precise mechanisms of action on the immune system are not fully understood. In particular, the early intratumoral immune responses induced by angiogenesis inhibition remain unclear.

Mots clés

Adaptive, Colorectal Cancer, Combination therapy, Immune Checkpoint Inhibitor, Natural killer - NK

Référence

J Immunother Cancer. 2026 06 22;14(6):