Fiche personne
Co-animateur du Conseil scientifique et clinique du Cancéropôle Est (COSC)
Coordonnées
Hôpital de Hautepierre
17 rue Albert Calmette
BP 23025
67033 STRASBOURG Cedex
03 68 76 66 66
Territoire
Alsace
Statut
Hospitalo-Universitaire
Affiliation
Hôpitaux universitaires de Strasbourg (HUS)
IGBMC - Institut de génétique et de biologie moléculaire et cellulaire (IGBMC)
Équipes/plateformes
Equipe "Génomique fonctionnelle et cancer / Régulation de l’expression génique et cancer"
Projets
Caractérisation multi-omique et spatiale à l'échelle de cellules uniques des hyperplasies idiopathiques diffuses des cellules neuroendocrines pulmonaires
2025 - Porteur du projet : Pr MALOUF Gabriel
Clarifier les mystères des cancers du rein à translocation: des modèles animaux aux thérapies ciblées
2024 - Porteur du projet : Pr MALOUF Gabriel
Interaction entre MYC et le complexe SWI/SNF dans les tumeurs SMARCB1-déficientes
2021 - Porteur du projet : Pr MALOUF Gabriel
Analyse intégrative des altérations épigénétiques des tumeurs desmoïdes: étude ancillaire de l'essai clinique national, multicentrique (CRYODESMO-1)
2020 - Porteur du projet : Dr GANTZER Justine - Partenaire : Pr GANGI Afshin , Pr KURTZ Jean-Emmanuel , Pr MALOUF Gabriel
Caractérisation moléculaire intégrative des cancers du rein à translocation de la famille MIT
2019 - Porteur du projet : Pr MALOUF Gabriel
Utilisation de l’épigénétique comme un outil pour prédire la réponse à l’immunothérapie chez les patients ayant un cancer du rein
2018 - Porteur du projet : Pr MALOUF Gabriel
Publications
Normal organ [Ga]DOTATOC uptake during PRRT: challenging the assumption of stable background shaped by cold somatostatin analogues treatment.
Ait Talhiq H, Baltzinger P, Frega J, Collen C, Colin Valentin M, Malouf GG, Porot C, Abdelghani MB, Addeo P, Goichot B, Berti V, Imperiale A
Eur J Nucl Med Mol Imaging. 2025 11 15;:
Racial differences in kidney cancer histology and outcome: A nationwide study from the UroCCR Cohort.
Lu X, Bernhard JC, Margue G, Audenet F, Doumerc N, Merlin P, Roupret M, Waeckel T, Champy C, Surlemont L, Olivier J, Branger N, Parier B, Gaillard V, Bruyere F, Fontenil A, Michel C, Vignot L, Descotes JL, Loison G, Guillotreau J, Taha F, Panthier F, De Vergie S, Ouzaid I, Boissier R, Patard JJ, Gimel P, Duquesne I, Chalhoub K, Bigot P, Malouf GG
Cancer. 2025 10 15;131(20):e70120
Prospective Analysis of Mesotheliomas in Subjects with BAP1 Cancer Syndrome: Clinical Characteristics and Epigenetic Correlates of Disease.
Wu X, Hernandez FV, Wang H, Wang R, Shiffka S, Shah N, Carr SR, Hoang CD, Blakely AM, Lebensohn A, Mihsra K, Xi S, Zhang MR, Tolunay T, Gara S, Absher A, Francis D, Rowland A, Connolly M, Jacobs S, Orfgen S, Driscoll K, Ghafoor A, Lu X, Malouf GG, Yang H, Carbone M, Hassan R, Jones E, Miettinen M, Schrump DS
J Thorac Oncol. 2025 08 5;:
Enhanced efficacy of ipilimumab plus nivolumab in angiogenic subtypes of metastatic clear-cell renal cell carcinoma.
Lu X, Vano YA, Su X, Verkarre V, Sun CM, Cheng W, Xu L, Yan F, Kotti S, Fridman WH, Sautes-Fridman C, Oudard S, Malouf GG
NPJ Precis Oncol. 2025 05 8;9(1):134
EGFR-Mutant Urothelial Carcinoma Harboring an Ala750_Ile759delinsGlyGly Alteration with a Primary Resistance to Polychemotherapy and a Sensitivity to Osimertinib: A Literature Review on EGFR Alterations and Response to EGFR Tyrosine Kinase Inhibitors in C
Barbe-Richaud JB, Fattori A, Lindner V, Schuster C, Malouf G, Pencreach E, Somme L
J Clin Med. 2025 04 30;14(9):
TFE3 fusions drive oxidative metabolism and ferroptosis resistance in translocation renal cell carcinoma.
Helleux A, Davidson G, Lallement A, Hourani FA, Haller A, Michel I, Fadloun A, Thibault-Carpentier C, Su X, Lindner V, Tricard T, Lang H, Tannir NM, Davidson I, Malouf GG
EMBO Mol Med. 2025 03 27;:
Stratification system with dual human endogenous retroviruses for predicting immunotherapy efficacy in metastatic clear-cell renal cell carcinoma.
Lu X, Vano YA, Su X, Verkarre V, Sun CM, Cheng W, Xu L, Yan F, Kotti S, Fridman WH, Sautes-Fridman C, Oudard S, Malouf GG
J Immunother Cancer. 2025 01 22;13(1):
Organ-specific response to [Lu]DOTATATE peptide receptor radionuclide therapy (PRRT) assessed by sequential [Ga]DOTATOC PET/CT in patients with metastatic small intestine neuroendocrine tumors.
Mamulashvili Bessac D, Baltzinger P, Poterszman N, Pham Van F, Collen C, Malouf GG, Ouvrard E, Kaseb A, Porot C, Ben Abdelghani M, Addeo P, Mertz L, Goichot B, Imperiale A
Endocrine. 2024 12 23;:
Effect of Treatment of Residual Disease After Immunotherapy-Based Combinations on Complete Response Rate of Patients With Metastatic Renal Cell Carcinomas.
Moinard-Butot F, Oriel M, Tricard T, Cazzato RL, Pierard L, Gaillard V, Werle P, Lindner V, Martin S, Schuster C, Roy C, Burgy M, Anthony A, Bigot C, Boudier P, Fritsch A, Olland A, Malouf G, Lang H, Barthélémy P
Clin Genitourin Cancer. 2024 06 5;22(5):102134
PEC-PRO: A new prognostic score from a series of 87 patients with localized perivascular epithelioid cell neoplasms (PEComas) treated with curative intent.
Gantzer J, Toulmonde M, Severac F, Chamseddine AN, Charon-Barra C, Vinson C, Hervieu A, Bourgmayer A, Bertucci F, Ryckewaert T, Valentin T, Firmin N, Chaigneau L, Bompas E, Follana P, Rioux-Leclercq N, Soibinet-Oudot P, Bozec L, Le Loarer F, Weingertner N, Chevreau C, Duffaud F, Blay JY, Kurtz JE, Schöffski P, Brahmi M, Malouf GG
Cancer. 2024 03 12;:
Delineating the interplay between oncogenic pathways and immunity in anaplastic Wilms tumors.
Su X, Lu X, Bazai SK, Dainese L, Verschuur A, Dumont B, Mouawad R, Xu L, Cheng W, Yan F, Irtan S, Lindner V, Paillard C, Le Bouc Y, Coulomb A, Malouf GG
Nat Commun. 2023 11 30;14(1):7884
Silencing of genes by promoter hypermethylation shapes tumor microenvironment and resistance to immunotherapy in clear-cell renal cell carcinomas.
Lu X, Vano YA, Su X, Helleux A, Lindner V, Mouawad R, Spano JP, Rouprêt M, Compérat E, Verkarre V, Sun CM, Bennamoun M, Lang H, Barthelemy P, Cheng W, Xu L, Davidson I, Yan F, Fridman WH, Sautes-Fridman C, Oudard S, Malouf GG
Cell Rep Med. 2023 11 8;:101287
Mesenchymal-like tumor cells and myofibroblastic cancer-associated fibroblasts are associated with progression and immunotherapy response of clear-cell renal cell carcinoma.
Davidson G, Helleux A, Vano YA, Lindner V, Fattori A, Cerciat M, Elaidi RT, Verkarre V, Sun CM, Chevreau C, Bennamoun M, Lang H, Tricard T, Fridman WH, Sautes-Fridman C, Su X, Plassard D, Keime C, Thibault-Carpentier C, Barthélémy P, Oudard SM, Davidson I, Malouf GG
Cancer Res. 2023 06 19;:
Racial Disparities in MiT Family Translocation Renal Cell Carcinoma.
Lu X, Tawanaie Pour Sedehi N, Su X, Yan F, Alhalabi O, Tannir NM, Malouf GG
Oncologist. 2023 06 14;:
SMARCB1 regulates a TFCP2L1-MYC transcriptional switch promoting renal medullary carcinoma transformation and ferroptosis resistance.
Vokshi BH, Davidson G, Tawanaie Pour Sedehi N, Helleux A, Rippinger M, Haller AR, Gantzer J, Thouvenin J, Baltzinger P, Bouarich R, Manriquez V, Zaidi S, Rao P, Msaouel P, Su X, Lang H, Tricard T, Lindner V, Surdez D, Kurtz JE, Bourdeaut F, Tannir NM, Davidson I, Malouf GG
Nat Commun. 2023 05 26;14(1):3034
Immune Checkpoint Therapy Combinations in Adult Advanced MiT Family Translocation Renal Cell Carcinomas.
Alhalabi O, Thouvenin J, Négrier S, Vano YA, Campedel L, Hasanov E, Bakouny Z, Hahn AW, Bilen MA, Msaouel P, Choueiri TK, Viswanathan SR, Sircar K, Albiges L, Malouf GG, Tannir NM
Oncologist. 2023 01 14;:
Molecular analysis for refractory rare cancers: Sequencing battle continues - learnings for the MOSCATO-01 study.
Debien V, Vignot S, Massard C, Malouf G, Hollebecque A, Scoazec JY, Michiels S, Verlingue L
Crit Rev Oncol Hematol. 2022 11 29;181:103888
An enhancer demethylator phenotype converged to immune dysfunction and resistance to immune checkpoint inhibitors in clear-cell renal cell carcinomas.
Lu X, Vano Y, Helleux A, Su X, Lindner V, Davidson G, Mouawad R, Spano JP, Roupret M, Elaidi R, Compérat E, Verkarre V, Sun C, Chevreau C, Bennamoun M, Lang H, Tricard T, Cheng W, Xu L, Davidson I, Yan F, Fridman WH, Sautes-Fridman C, Oudard S, Malouf GG
Clin Cancer Res. 2022 11 14;:
The lncRNA LENOX interacts with RAP2C to regulate metabolism and promote resistance to MAPK inhibition in melanoma.
Gambi G, Mengus G, Davidson G, Demesmaeker E, Cuomo A, Bonaldi T, Katopodi V, Malouf GG, Leucci E, Davidson I
Cancer Res. 2022 10 10;:
Efficacy of Cabozantinib in Metastatic MiT Family Translocation Renal Cell Carcinomas.
Thouvenin J, Alhalabi O, Carlo M, Carril-Ajuria L, Hirsch L, Martinez-Chanza N, Négrier S, Campedel L, Martini D, Borchiellini D, Chahoud J, Lodi M, Barthélémy P, Hasanov E, Hahn AW, Gil T, Viswanathan SR, Bakouny Z, Msaouel P, Asim Bilen M, Choueiri TK, Albiges L, Tannir NM, Malouf GG
Oncologist. 2022 08 18;:
Genetic landscape of indolent and aggressive Kaposi sarcomas.
Malouf GG, Lu X, Mouawad R, Spano JP, Grange P, Yan F, Aractingi S, Su X, Dupin N
J Eur Acad Dermatol Venereol. 2022 07 26;:
[New drug approval: Adjuvant Pembrolizumab in clear-cell renal-cell carcinomaat high risk for recurrence after nephrectomy].
Brunet M, Malouf GG
Bull Cancer. 2022 06 28;:
Impact of the app-based and nurse-led supportive care program AKO@dom on dose intensity of oral-targeted therapies in patients with metastatic renal cell cancer: a multicentric observational retrospective study.
Gaillard V, Lhuillier A, Bigot C, Pierard L, Trensz P, Burgy M, Schuster C, Malouf G, Fritsch A, Lang H, Tricard T, Borchiellini D, Geoffrois L, Barthelemy P
Support Care Cancer. 2022 Apr 29;:
Immune-Desert Tumor Microenvironment in Thoracic SMARCA4-Deficient Undifferentiated Tumors with Limited Efficacy of Immune Checkpoint Inhibitors.
Gantzer J, Davidson G, Vokshi B, Weingertner N, Bougoüin A, Moreira M, Lindner V, Lacroix G, Mascaux C, Chenard MP, Bertucci F, Davidson I, Kurtz JE, Sautès-Fridman C, Fridman WH, Malouf GG
Oncologist. 2022 Mar 12;:
Renal cell carcinoma in children and adolescents: A retrospective study of a French-Italian series of 93 cases.
Denize T, Massa S, Valent A, Militti L, Bertolotti A, Barisella M, Rioux-Leclercq N, Malouf GG, Spreafico F, Verschuur A, van der Beek J, Tytgat L, van den Heuvel-Eibrink MM, Vujanic G, Collini P, Coulomb A
Histopathology. 2022 Mar 3;:
Should pituitary carcinoma be treated using a NET-like approach? A case of complete remission of a metastatic malignant prolactinoma with multimodal therapy including immunotherapy.
Goichot B, Taquet MC, Baltzinger P, Baloglu S, Gravaud M, Malouf GG, Noël G, Imperiale A
Clin Endocrinol (Oxf). 2021 Nov 29;:
First-Line Treatment of Metastatic Clear Cell Renal Cell Carcinoma: What Are the Most Appropriate Combination Therapies?
Vano YA, Ladoire S, Elaidi R, Dermeche S, Eymard JC, Falkowski S, Gross-Goupil M, Malouf G, Narciso B, Sajous C, Tartas S, Voog E, Ravaud A
Cancers (Basel). 2021 Nov 5;13(21):
Natural History and Treatment Strategies of Advanced PEComas: A Systematic Review.
Bourgmayer A, Nannini S, Bonjean P, Kurtz JE, Malouf GG, Gantzer J
Cancers (Basel). 2021 Oct 18;13(20):
Efficacy of Immune Checkpoint Inhibitors in Upper Tract Urothelial Carcinomas: Current Knowledge and Future Directions.
Thouvenin J, Martínez Chanzá N, Alhalabi O, Lang H, Tannir NM, Barthélémy P, Malouf GG
Cancers (Basel). 2021 Aug 27;13(17):
Involvement of Neutrophils in Metastatic Evolution of Pancreatic Neuroendocrine Tumors.
Debien V, Davidson G, Baltzinger P, Kurtz JE, Séverac F, Imperiale A, Pessaux P, Addeo P, Bachellier P, Su X, Davidson I, Chenard MP, Goichot B, Malouf GG
Cancers (Basel). 2021 Jun 2;13(11):
Addressing resistance to immune checkpoint inhibitor therapy - an urgent unmet need.
Hu-Lieskovan S, Malouf GG, Jacobs I, Chou J, Liu L, Johnson ML
Future Oncol. 2021 Jan 21;:
Comprehensive integrative profiling of upper tract urothelial carcinomas.
Su X, Lu X, Bazai SK, Compérat E, Mouawad R, Yao H, Rouprêt M, Spano JP, Khayat D, Davidson I, Tannir NN, Yan F, Malouf GG
Genome Biol. 2021 Jan 4;22(1):7
French Multidisciplinary Approach for the Treatment of MSK Tumors.
Cazzato RL, Garnon J, De Marini P, Auloge P, Dalili D, Koch G, Antoni D, Barthelemy P, Kurtz JE, Malouf G, Feydy A, Charles YP, Gangi A
Semin Musculoskelet Radiol. 2020 Jun;24(3):310-322
The Promise for Histone Methyltransferase Inhibitors for Epigenetic Therapy in Clinical Oncology: A Narrative Review.
Rugo HS, Jacobs I, Sharma S, Scappaticci F, Paul TA, Jensen-Pergakes K, Malouf GG
Adv Ther. 2020 May 22;:
Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma.
Msaouel P, Malouf GG, Su X, Yao H, Tripathi DN, Soeung M, Gao J, Rao P, Coarfa C, Creighton CJ, Bertocchio JP, Kunnimalaiyaan S, Multani AS, Blando J, He R, Shapiro DD, Perelli L, Srinivasan S, Carbone F, Pilié PG, Karki M, Seervai RNH, Vokshi BH, Lopez-Terrada D, Cheng EH, Tang X, Lu W, Wistuba II, Thompson TC, Davidson I, Giuliani V, Schlacher K, Carugo A, Heffernan TP, Sharma P, Karam JA, Wood CG, Walker CL, Genovese G, Tannir NM
Cancer Cell. 2020 Apr 15;:
[MiT family translocation renal cell carcinomas: Natural history, molecular features and multidisciplinary management].
Herrscher H, Boilève A, Lindner V, Barthélémy P, Hutt É, Pierard L, Kurtz JE, Rioux-Leclercq N, Lang H, Malouf GG
Bull Cancer. 2020 Feb 7;:
Molecular characterization of sarcomatoid clear cell renal cell carcinoma unveils new candidate oncogenic drivers.
Malouf GG, Flippot R, Dong Y, Dinatale RG, Chen YB, Su X, Compérat E, Rouprêt M, Mano R, Blum KA, Yao H, Mouawad R, Spano JP, Khayat D, Karam JA, Ho TH, Tickoo SK, Russo P, Hsieh JJ, Tannir NM, Hakimi AA
Sci Rep. 2020 Jan 20;10(1):701
Sarcomatoid Dedifferentiation in Renal Cell Carcinoma: From Novel Molecular Insights to New Clinical Opportunities.
Debien V, Thouvenin J, Lindner V, Barthélémy P, Lang H, Flippot R, Malouf GG
Cancers (Basel). 2019 Dec 31;12(1):
Heart failure and atrial tachyarrhythmia on abiraterone: A pharmacovigilance study.
Bretagne M, Lebrun-Vignes B, Pariente A, Shaffer CM, Malouf GG, Dureau P, Potey C, Funck-Brentano C, Roden DM, Moslehi JJ, Salem JE
Arch Cardiovasc Dis. 2019 Nov 1;:
[Epigenetic alterations in kidney cancers].
Helleux A, Debien V, Fadloun A, Rippinger M, Lebedinsky S, Davidson I, Malouf GG
Bull Cancer. 2019 Aug 23;:
Lack of efficacy of neoadjuvant chemotherapy in adult patients with maxillo-facial high-grade osteosarcomas: A French experience in two reference centers.
Bouaoud J, Beinse G, Epaillard N, Amor-Sehlil M, Bidault F, Brocheriou I, Hervé G, Spano JP, Janot F, Boudou-Rouquette P, Benassarou M, Schouman T, Goudot P, Malouf G, Goldwasser F, Bertolus C
Oral Oncol.. 2019 Aug;95:79-86
Evaluating the prognostic potential of the Ki67 index and tumor infiltrating lymphocytes in olfactory neuroblastoma.
Classe M, Burgess A, El Zein S, Wassef M, Herman P, Mortuaire G, Leroy X, Malouf GG, Verillaud B
Histopathology. 2019 Jul 15;:
Long non-coding RNAs in genitourinary malignancies: a whole new world.
Flippot R, Beinse G, Boilève A, Vibert J, Malouf GG
Nat Rev Urol. 2019 May 20;:
Stereotactic Radiation Therapy for Renal Cell Carcinoma Brain Metastases in the Tyrosine Kinase Inhibitors Era: Outcomes of 120 Patients.
Klausner G, Troussier I, Biau J, Jacob J, Schernberg A, Canova CH, Simon JM, Borius PY, Malouf G, Spano JP, Roupret M, Cornu P, Mazeron JJ, Valéry C, Feuvret L, Maingon P
Clin Genitourin Cancer. 2019 Feb 28;:
Dynamic evolution of clonal composition and neoantigen landscape in recurrent metastatic melanoma with a rare combination of driver mutations.
Davidson G, Coassolo S, Kieny A, Ennen M, Pencreach E, Malouf GG, Lipsker D, Davidson I
J. Invest. Dermatol.. 2019 Feb 15;:
p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors.
Carugo A, Minelli R, Sapio L, Soeung M, Carbone F, Robinson FS, Tepper J, Chen Z, Lovisa S, Svelto M, Amin S, Srinivasan S, Del Poggetto E, Loponte S, Puca F, Dey P, Malouf GG, Su X, Li L, Lopez-Terrada D, Rakheja D, Lazar AJ, Netto GJ, Rao P, Sgambato A, Maitra A, Tripathi DN, Walker CL, Karam JA, Heffernan TP, Viale A, Roberts CWM, Msaouel P, Tannir NM, Draetta GF, Genovese G
Cancer Cell. 2019 Feb 11;35(2):204-220.e9
Brain Metastases and Place of Antiangiogenic Therapies in Alveolar Soft Part Sarcoma: A Retrospective Analysis of the French Sarcoma Group.
Malouf GG, Beinse G, Adam J, Mir O, Chamseddine AN, Terrier P, Honore C, Spano JP, Italiano A, Kurtz JE, Coindre JM, Blay JY, Le Cesne A
Oncologist. 2019 Jan 9;:
Immune checkpoint inhibitors in MITF family translocation renal cell carcinomas and genetic correlates of exceptional responders.
Boilève A, Carlo MI, Barthélémy P, Oudard S, Borchiellini D, Voss MH, George S, Chevreau C, Landman-Parker J, Tabone MD, Chism DD, Amin A, Bilen MA, Bosse D, Coulomb-L'hermine A, Su X, Choueiri TK, Tannir NM, Malouf GG
J Immunother Cancer. 2018 Dec 27;6(1):159
Integrated Multi-omic Analysis of Esthesioneuroblastomas Identifies Two Subgroups Linked to Cell Ontogeny.
Classe M, Yao H, Mouawad R, Creighton CJ, Burgess A, Allanic F, Wassef M, Leroy X, Verillaud B, Mortuaire G, Bielle F, Le Tourneau C, Kurtz JE, Khayat D, Su X, Malouf GG
Cell Rep. 2018 Oct 16;25(3):811-821.e5
Metabolic Response to BRAF-MEK Combination Therapy in Cecal Neuroendocrine Carcinoma With BRAFV600E Mutation and Refractory Lactic Acidosis.
Imperiale A, Latgé A, Schaff-Wendling F, Goichot B, Kurtz JE, Malouf GG
Clin Nucl Med. 2018 Jul 21;:
Papillary Renal Cell Carcinoma: A Family Portrait.
Flippot R, Compérat E, Tannir NM, Malouf GG
Eur. Urol.. 2018 01;73(1):79-80
Management and outcomes of patients with renal medullary carcinoma: a multicentre collaborative study.
Shah AY, Karam JA, Malouf GG, Rao P, Lim ZD, Jonasch E, Xiao L, Gao J, Vaishampayan UN, Heng DY, Plimack ER, Guancial EA, Fung C, Lowas SR, Tamboli P, Sircar K, Matin SF, Kimryn Rathmell W, Wood CG, Tannir NM
BJU Int.. 2017 12;120(6):782-792
Recommendations for the Management of Rare Kidney Cancers.
Giles RH, Choueiri TK, Heng DY, Albiges L, Hsieh JJ, Linehan WM, Pal S, Maskens D, Paseman B, Jonasch E, Malouf G, Molina AM, Pickering L, Shuch B, Srinivas S, Srinivasan R, Tannir NM, Bex A
Eur. Urol.. 2017 Dec;72(6):974-983
Inactivation and Mutation Drive a Convergence toward Loss of Function of H3K36 Writers in Clear Cell Renal Cell Carcinomas.
Su X, Zhang J, Mouawad R, Compérat E, Rouprêt M, Allanic F, Parra J, Bitker MO, Thompson EJ, Gowrishankar B, Houldsworth J, Weinstein JN, Tost J, Broom BM, Khayat D, Spano JP, Tannir NM, Malouf GG
Cancer Res.. 2017 09 15;77(18):4835-4845
Safety of treatment with nivolumab after ipilimumab-related meningoradiculitis and bilateral optic neuropathy.
Boisseau W, Touat M, Berzero G, Savatovsky J, Marabelle A, Touitou V, Ricard D, Malouf G, Psimaras D
Eur. J. Cancer. 2017 09;83:28-31
[Neuroendocrine prostate cancer: Natural history, molecular features, therapeutic management and future directions].
Campedel L, Kossaï M, Blanc-Durand P, Rouprêt M, Seisen T, Compérat E, Spano JP, Malouf G
Bull Cancer. 2017 Sep;104(9):789-799
Expression of long non-coding RNA MFI2-AS1 is a strong predictor of recurrence in sporadic localized clear-cell renal cell carcinoma.
Flippot R, Mouawad R, Spano JP, Rouprêt M, Compérat E, Bitker MO, Parra J, Vaessen C, Allanic F, Manach Q, Tannir NM, Khayat D, Su X, Malouf GG
Sci Rep. 2017 Aug 17;7(1):8540
Renal Medullary Carcinoma: Establishing Standards in Practice.
Beckermann KE, Sharma D, Chaturvedi S, Msaouel P, Abboud MR, Allory Y, Bourdeaut F, Calderaro J, de Cubas AA, Derebail VK, Hong AL, Naik RP, Malouf GG, Mullen EA, Reuter VE, Roberts CWM, Walker CL, Wood CG, DeBaun MR, Van Poppel H, Tannir NM, Rathmell WK
J Oncol Pract. 2017 Jul;13(7):414-421
Incidence, clinicopathological features and fusion transcript landscape of translocation renal cell carcinomas.
Classe M, Malouf GG, Su X, Yao H, Thompson EJ, Doss DJ, Grégoire V, Lenobin J, Fantoni JC, Sudour-Bonnange H, Khayat D, Aubert S, Tannir NM, Leroy X
Histopathology. 2017 Jun;70(7):1089-1097
Non-clear cell renal cell carcinomas: biological insights and therapeutic challenges and opportunities.
Malouf GG, Joseph RW, Shah AY, Tannir NM
Clin Adv Hematol Oncol. 2017 May;15(5):409-418
Linking Gene Mutations to Clinical Outcomes and Response to Therapy in Clear-cell Renal Cell Carcinoma: Ready for Prime Time?
Msaouel P, Malouf GG, Tannir NM
Eur. Urol.. 2017 03;71(3):415-416
Expression of human endogenous retrovirus-K is strongly associated with the basal-like breast cancer phenotype.
Johanning GL, Malouf GG, Zheng X, Esteva FJ, Weinstein JN, Wang-Johanning F, Su X
Sci Rep. 2017 02 6;7:41960
Repositioning FDA-Approved Drugs in Combination with Epigenetic Drugs to Reprogram Colon Cancer Epigenome.
Raynal NJ, Da Costa EM, Lee JT, Gharibyan V, Ahmed S, Zhang H, Sato T, Malouf GG, Issa JJ
Mol. Cancer Ther.. 2017 02;16(2):397-407
DNA Methylation Signature Reveals Cell Ontogeny of Renal Cell Carcinomas.
Malouf GG, Su X, Zhang J, Creighton CJ, Ho TH, Lu Y, Raynal NJ, Karam JA, Tamboli P, Allanick F, Mouawad R, Spano JP, Khayat D, Wood CG, Jelinek J, Tannir NM
Clin. Cancer Res.. 2016 Dec 15;22(24):6236-6246
Modelling TFE renal cell carcinoma in mice reveals a critical role of WNT signaling.
Calcagnì A, Kors L, Verschuren E, De Cegli R, Zampelli N, Nusco E, Confalonieri S, Bertalot G, Pece S, Settembre C, Malouf GG, Leemans JC, de Heer E, Salvatore M, Peters DJ, Di Fiore PP, Ballabio A
Elife. 2016 Sep 26;5:
Cancer subtypes classification using long non-coding RNA.
Flippot R, Malouf GG, Su X, Mouawad R, Spano JP, Khayat D
Oncotarget. 2016 Aug 16;7(33):54082-54093
Genomic Characterization of Renal Cell Carcinoma with Sarcomatoid Dedifferentiation Pinpoints Recurrent Genomic Alterations.
Malouf GG, Ali SM, Wang K, Balasubramanian S, Ross JS, Miller VA, Stephens PJ, Khayat D, Pal SK, Su X, Sircar K, Tamboli P, Jonasch E, Tannir NM, Wood CG, Karam JA
Eur. Urol.. 2016 08;70(2):348-57
Unique Transcriptomic Profile of Collecting Duct Carcinomas Relative to Upper Tract Urothelial Carcinomas and other Kidney Carcinomas.
Malouf GG, Compérat E, Yao H, Mouawad R, Lindner V, Rioux-Leclercq N, Verkarre V, Leroy X, Dainese L, Classe M, Descotes JL, Barthelemy P, Yacoub M, Rouprêt M, Bernhard JC, Creighton CJ, Spano JP, Su X, Khayat D
Sci Rep. 2016 Aug;6:30988
A comprehensive review of genomic landscape, biomarkers and treatment sequencing in castration-resistant prostate cancer.
Seisen T, Rouprêt M, Gomez F, Malouf GG, Shariat SF, Peyronnet B, Spano JP, Cancel-Tassin G, Cussenot O
Cancer Treat. Rev.. 2016 Jul;48:25-33
Oncogenic viruses: Lessons learned using next-generation sequencing technologies.
Flippot R, Malouf GG, Su X, Khayat D, Spano JP
Eur. J. Cancer. 2016 07;61:61-8
Therapeutic Strategies for Patients With Metastatic Renal Cell Carcinoma in Whom First-Line Vascular Endothelial Growth Factor Receptor-Directed Therapies Fail.
Malouf GG, Flippot R, Khayat D
J Oncol Pract. 2016 05;12(5):412-20
Targeting Calcium Signaling Induces Epigenetic Reactivation of Tumor Suppressor Genes in Cancer.
Raynal NJ, Lee JT, Wang Y, Beaudry A, Madireddi P, Garriga J, Malouf GG, Dumont S, Dettman EJ, Gharibyan V, Ahmed S, Chung W, Childers WE, Abou-Gharbia M, Henry RA, Andrews AJ, Jelinek J, Cui Y, Baylin SB, Gill DL, Issa JP
Cancer Res.. 2016 Mar 15;76(6):1494-505
Long non-coding RNA profiling links subgroup classification of endometrioid endometrial carcinomas with trithorax and polycomb complex aberrations.
Jiang Y, Malouf GG, Zhang J, Zheng X, Chen Y, Thompson EJ, Weinstein JN, Yuan Y, Spano JP, Broaddus R, Tannir NM, Khayat D, Lu KH, Su X
Oncotarget. 2015 Nov 24;6(37):39865-76
Characterization of long non-coding RNA transcriptome in clear-cell renal cell carcinoma by next-generation deep sequencing.
Malouf GG, Zhang J, Yuan Y, Compérat E, Rouprêt M, Cussenot O, Chen Y, Thompson EJ, Tannir NM, Weinstein JN, Valero V, Khayat D, Spano JP, Su X
Mol Oncol. 2015 Jan;9(1):32-43
Methylome sequencing for fibrolamellar hepatocellular carcinoma depicts distinctive features.
Malouf GG, Tahara T, Paradis V, Fabre M, Guettier C, Yamazaki J, Long H, Lu Y, Raynal NJ, Jelinek J, Mouawad R, Khayat D, Brugières L, Raymond E, Issa JP
Epigenetics. 2015 ;10(9):872-81
Comprehensive analysis of long non-coding RNAs in human breast cancer clinical subtypes.
Su X, Malouf GG, Chen Y, Zhang J, Yao H, Valero V, Weinstein JN, Spano JP, Meric-Bernstam F, Khayat D, Esteva FJ
Oncotarget. 2014 Oct 30;5(20):9864-76
Is histological diagnosis of primary liver carcinomas with fibrous stroma reproducible among experts?
Malouf G, Falissard B, Azoulay D, Callea F, Ferrell LD, Goodman ZD, Hayashi Y, Hsu HC, Hubscher SG, Kojiro M, Ng IO, Paterson AC, Reynes M, Zafrani ES, Emile JF
J. Clin. Pathol.. 2009 Jun;62(6):519-24