Fiche publication
Date publication
juin 2026
Journal
European journal of cancer (Oxford, England : 1990)
Auteurs
Membres identifiés du Cancéropôle Est :
Pr CHENARD Marie-Pierre
,
Pr GANGI Afshin
,
Pr KURTZ Jean-Emmanuel
,
Pr SAULEAU Erik-André
,
Pr MALOUF Gabriel
,
Dr GANTZER Justine
Tous les auteurs :
Gantzer J, Lu X, Weingertner N, Fattori A, Chenard MP, Plassard D, El Amri A, Sauleau EA, Gangi A, Kurtz JE, Malouf GG
Lien Pubmed
Résumé
Desmoid tumors (DTs) are locally aggressive soft tissue neoplasms with variable clinical behavior and limited therapeutic biomarkers. While CTNNB1 and APC mutations are known, the broader genomic, transcriptomic, and epigenetic features remain incompletely understood.
Mots clés
Chromatin remodeling genes, Comprehensive molecular profiling, Desmoid tumor, Myogenic background, Tumor microenvironment
Référence
Eur J Cancer. 2026 06 20;244:116905