Fiche publication


Date publication

juin 2026

Journal

European journal of cancer (Oxford, England : 1990)

Auteurs

Membres identifiés du Cancéropôle Est :
Pr CHENARD Marie-Pierre , Pr GANGI Afshin , Pr KURTZ Jean-Emmanuel , Pr SAULEAU Erik-André , Pr MALOUF Gabriel , Dr GANTZER Justine


Tous les auteurs :
Gantzer J, Lu X, Weingertner N, Fattori A, Chenard MP, Plassard D, El Amri A, Sauleau EA, Gangi A, Kurtz JE, Malouf GG

Résumé

Desmoid tumors (DTs) are locally aggressive soft tissue neoplasms with variable clinical behavior and limited therapeutic biomarkers. While CTNNB1 and APC mutations are known, the broader genomic, transcriptomic, and epigenetic features remain incompletely understood.

Mots clés

Chromatin remodeling genes, Comprehensive molecular profiling, Desmoid tumor, Myogenic background, Tumor microenvironment

Référence

Eur J Cancer. 2026 06 20;244:116905