Exploring the one-pot C-acylation of cyclic 1,3-diones with unactivated carboxylic acid
Fiche publication
Date publication
avril 2010
Auteurs
Membres identifiés du Cancéropôle Est :
Dr WAGNER Alain
Tous les auteurs :
Goncalves S, Nicolas M, Wagner A, Baati R
Lien Pubmed
Résumé
The use of DCC, triethylamine, and 4-dimethylaminopyridine in dichloromethane provides a general and standard one-pot procedure for the C-acylation of cyclic 1,3-diones with a wide range of carboxylic acids, giving rise to beta-triketones in good to excellent yields. (C) 2010 Elsevier Ltd. All rights reserved.
Référence
Tetrahedron Lett. 2010 Apr 28;51(17):2348-50