An unexpected rearrangement giving a new thiosubstituted carbohydrate.
Fiche publication
Date publication
juin 2010
Auteurs
Membres identifiés du Cancéropôle Est :
Dr NUZILLARD Jean-Marc
Tous les auteurs :
Martinez A, Henon E, Coiffier C, Banchet A, Harakat D, Nuzillard JM, Haudrechy A
Lien Pubmed
Résumé
A new thiosubstituted 'd-arabino'-type derivative was obtained from an open carbohydrate via a cascade of four consecutive transformations in a single reaction process. Molecular orbital computations were also performed to explain the stereochemical outcome of the reaction.
Référence
Carbohydr Res. 2010 Jun 16;345(9):1088-93