High-resolution tomographic diffractive microscopy of biological samples.

Fiche publication


Date publication

juillet 2010

Auteurs

Membres identifiés du Cancéropôle Est :
Pr HAEBERLE Olivier


Tous les auteurs :
Simon B, Debailleul M, Beghin A, Tourneur Y, Haeberle O

Résumé

The authors have developed a tomographic diffractive microscope that combines microholography with illumination from an angular synthetic aperture. It images specimens relative to their complex index of refraction distribution (index and absorption) and permits imaging of unlabelled specimens, with high lateral resolution. The authors now study its use for biological applications, and imaged several preparations with fluorescence confocal microscopy and tomographic diffractive microscopy. The results highlight some interesting features of this instrument, which should attract the interest of biologists for this new technique.

Référence

J Biophotonics. 2010 Jul;3(7):462-7.