[Intrahospital mortality during acute exacerbations of COPD. Study EABPCO-CPHG of the College of the Lung specialists of General hospitals (CPHG)].

Fiche publication


Date publication

septembre 2010

Auteurs

Membres identifiés du Cancéropôle Est :
Dr DEBIEUVRE Didier


Tous les auteurs :
Chavaillon JM, Lerousseau L, David P, Martin F, Lamour C, Beraud A, Sleiman C, Debieuvre D, Just N, Senechal F, Camuset J, Mornet M, Fesq G, Zureik M, Roche N, Blanchon F, Piquet J

Résumé

INTRODUCTION: The objective of the present study was to determine the in-hospital mortality rate in the EAPCO-CPHG cohort and to identify risk factors. METHODS: All patients with COPD acute exacerbation admitted to the pneumology department of 68 French general hospitals between October 2006 and June 2007 were included in the EABPCO-CPHG cohort. RESULTS: At discharge, vital status was known for 1817 patients. Forty-five patients died during their hospital stay, i.e., an in-hospital mortality rate of 2.5%. Mutivariate analysis identified age (OR=1.07 [1.03-1.11]), grade greater than 2 dyspnea in stable state (OR=3.77 [1.68-8.57]), and number of clinical signs of severity during the acute exacerbation (OR=1.36 [1.11-1.55]) as independent risk factors for in-hospital mortality. CONCLUSIONS: In-hospital mortality in patients admitted to a pneumology department of a general hospital is quite low. Simple clinical criteria allow easy identification of at-risk patients and should enable management to be improved.

Référence

Rev Mal Respir. 2010 Sep;27(7):709-16