Unprecedented Elimination of Conjugated Phenylthioether Groups by Low-Valent Titanocene.
Fiche publication
Date publication
décembre 2010
Auteurs
Membres identifiés du Cancéropôle Est :
Dr DESAUBRY Laurent
Tous les auteurs :
Ribeiro N, Fetzer L, Streiff S, Desaubry L
Lien Pubmed
Résumé
The first thioether elimination reaction utilizing a low-valent titanocene has been discovered. This reaction occurs under mild conditions and affords stereospecifically a variety of dienes and styrenes. Our data suggest that this new reaction involves an intermediate of dimerization of titanocene as the reactant responsible for this elimination.
Référence
Synlett. 2010 Dec;19:2928-30.