Tailoring drug release profile of low-molecular-weight hydrogels by supramolecular co-assembly and thiol-ene orthogonal coupling.
Fiche publication
Date publication
janvier 2011
Auteurs
Membres identifiés du Cancéropôle Est :
Dr WAGNER Alain
Tous les auteurs :
Diaz DD, Morin E, Schon EM, Budin G, Wagner A, Remy JS
Lien Pubmed
Résumé
We describe a general user-friendly platform for fine-tuning the drug release properties of low-molecular-weight hydrogels by a combination of supramolecular co-assembly of complementary molecular structures and controlled photochemical thiol-ene cross-linking. Other critical features such as thermomechanical stability and morphology of the nanostructured hydrogels are also tailored by this approach.
Référence
. 2011;21(3):641-4.