The MEDICALIP Project: Toward the screening of the cytomegalovirus.

Fiche publication


Date publication

avril 2011

Auteurs

Membres identifiés du Cancéropôle Est :
Dr BOIREAU Wilfrid, Dr PAZART Lionel, Dr PIERALLI Christian, Dr WACOGNE Bruno


Tous les auteurs :
Wacogne B, Guerrini JS, Mangeat T, Benalia H, Pieralli C, Rouleau A, Boireau W, Coaquette A, Herbein G, Davrinche C, Pazart L

Résumé

Since rubella vaccine was established, cytomegalovirus infection has become the most frequent cause of congenital infections. The French Health Authority is urging a diagnosis at birth for newborns. Since no screening device is commercially available, a consortium has been established to set-up an original device. The project has been funded by the French National Research Agency. The device consists of a disposable cartridge containing the biological sample and the reactive liquids required for immuno-fluorescencence detection on a functionalized surface. It also consists of a mobile reader used to drive the fluids onto the biosensor and to ensure the optical measurement. Positive and negative samples can be discriminated with a fluorescence intensity ratio of 3. (C) 2011 Elsevier Masson SAS. All rights reserved.

Référence

. 2011 Apr;32(2):66-8.