Fully automated production of sodium [F]fluoride on AllInOne and miniAllInOne synthesizers.

Fiche publication


Date publication

mai 2015

Auteurs

Membres identifiés du Cancéropôle Est :
Pr KARCHER Gilles


Tous les auteurs :
Collet C, Otabashi M, Giacomelli F, Veran N, Karcher G, Chapleur Y, Lamande-Langle S

Résumé

A fully automated production of the imaging agent sodium [18F]fluoride ([18F]NaF) on two different modules commercialized by Trasis(R), the AllInOne and the miniAllInOne, is reported. Both modules allow to prepare [18F]NaF in good radiochemical yield (around 97%) in less than 4min with the same specifications. Quality control of [18F]NaF produced by this way was performed according to the US and European Pharmacopeia monograph requirements.

Référence

Appl Radiat Isot. 2015 May 14;102:87-92