[Isolated splenic peliosis: a case report].
Fiche publication
Date publication
octobre 2012
Auteurs
Membres identifiés du Cancéropôle Est :
Dr LINDNER Véronique, Dr DEBLIQUIS Agathe
Tous les auteurs :
Renard C, Baumann D, Thiriat S, Debliquis A, Lindner V, Thiebault S
Lien Pubmed
Résumé
Peliosis is a rare vascular lesion that is usually found in the liver, and less frequently in other hematolymphoid organs. We report a case of isolated splenic peliosis discovered in a 65-year-old man with an erysipelas and a thrombocytopenia. The computed tomography abdominal scan revealed an heterogen multinodular splenic mass. Splenectomy was performed and platelet counts returned to normal levels. The histopathologic examination revealed dilations of sinuses in the red pulp. The endothelial cells lining cavities stain for CD8 and CD31 but not for CD34. Splenic peliosis is a rare benign disease of unknown aetiology, which belongs to the group of vascular neoplasms of the spleen. The final diagnosis is based on the pathology examen. We review the histologic and immunohistochemical arguments of this diagnostic and expose the differential diagnoses.
Référence
Ann Pathol. 2012 Oct;32(5):379-83