First steps towards conformationally selective artificial lectins: the chair-boat discrimination by molecularly imprinted polymers.
Fiche publication
Date publication
novembre 2012
Auteurs
Membres identifiés du Cancéropôle Est :
Dr WAGNER Alain
Tous les auteurs :
de Talance VL, Massinon O, Baati R, Wagner A, Vincent SP
Lien Pubmed
Résumé
A series of molecularly imprinted polymers (MIPs) were prepared in the presence of a synthetic galactoside locked in a (1,4)B boat conformation. This study demonstrates that, depending on the polymerisation technique, an organic material can selectively bind a carbohydrate in a biologically relevant boat conformation.
Référence
Chem Commun (Camb). 2012 Nov 7;48(86):10684-6