The vertebrate diencephalic MCH system: a versatile neuronal population in an evolving brain.
Fiche publication
Date publication
avril 2013
Auteurs
Membres identifiés du Cancéropôle Est :
Pr FELLMANN Dominique
Tous les auteurs :
Croizier S, Cardot J, Brischoux F, Fellmann D, Griffond B, Risold PY
Lien Pubmed
Résumé
Neurons synthesizing melanin-concentrating hormone (MCH) are described in the posterior hypothalamus of all vertebrates investigated so far. However, their anatomy is very different according to species: they are small and periventricular in lampreys, cartilaginous fishes or anurans, large and neuroendocrine in bony fishes, or distributed over large regions of the lateral hypothalamus in many mammals. An analysis of their comparative anatomy alongside recent data about the development of the forebrain, suggests that although very different, MCH neurons of the caudal hypothalamus are homologous. We further hypothesize that their divergent anatomy is linked to divergence in the forebrain - in particular telencephalic evolution.
Référence
Front Neuroendocrinol. 2013 Apr;34(2):65-87