Cyclophosphamide vs rituximab for eradicating inhibitors in acquired hemophilia A: A randomized trial in 108 patients.

Fiche publication


Date publication

mars 2024

Journal

Thrombosis research

Auteurs

Membres identifiés du Cancéropôle Est :
Pr BONNOTTE Bernard


Tous les auteurs :
Lévesque H, Viallard JF, Houivet E, Bonnotte B, Voisin S, Le Cam-Duchez V, Maillot F, Lambert M, Liozon E, Hervier B, Fain O, Guillet B, Schmidt J, Luca LE, Ebbo M, Ferreira-Maldent N, Babuty A, Sailler L, Duffau P, Barbay V, Audia S, Benichou J, Graveleau J, Benhamou Y,

Résumé

Acquired hemophilia A (AHA) is a rare autoimmune disorder due to autoantibodies against Factor VIII, with a high mortality risk. Treatments aim to control bleeding and eradicate antibodies by immunosuppression. International recommendations rely on registers and international expert panels.

Mots clés

Acquired hemophilia, Cyclophosphamide, Randomized trial, Rituximab

Référence

Thromb Res. 2024 03 15;237:79-87