A Prospective Randomized Trial of Neoadjuvant Chemohormonal Therapy vs Hormonal Therapy in Locally Advanced Prostate Cancer Treated by Radical Prostatectomy.
Fiche publication
Date publication
mai 2024
Journal
The Journal of urology
Auteurs
Membres identifiés du Cancéropôle Est :
Dr TRICARD Thibault
Tous les auteurs :
Qian H, Chi C, Tricard T, Zhu Y, Dong L, Wang Y, Sha J, Wang J, Ma Z, Wang Y, Liu J, Dong B, Pan J, Xue W
Lien Pubmed
Résumé
Benefits of docetaxel-based neoadjuvant chemohormonal therapy (NCHT) before radical prostatectomy (RP) remain largely unknown. We explored whether docetaxel-based NCHT would bring pathological benefits and improve biochemical progression-free survival (bPFS) over neoadjuvant hormonal therapy (NHT) in locally advanced prostate cancer.
Mots clés
biochemical recurrence, extended pelvic lymph node dissection, neoadjuvant chemohormonal therapy, radical prostatectomy
Référence
J Urol. 2024 05;211(5):648-655