DEAD box RNA helicase 5 is a new pro-viral host factor for Sindbis virus infection.
Fiche publication
Date publication
mars 2024
Journal
Virology journal
Auteurs
Membres identifiés du Cancéropôle Est :
Dr PFEFFER Sébastien, Mr HAMMANN Philippe
Tous les auteurs :
Messmer M, Pierson L, Pasquier C, Djordjevic N, Chicher J, Hammann P, Pfeffer S, Girardi E
Lien Pubmed
Résumé
RNA helicases are emerging as key factors regulating host-virus interactions. The DEAD-box ATP-dependent RNA helicase DDX5, which plays an important role in many aspects of cellular RNA biology, was also found to either promote or inhibit viral replication upon infection with several RNA viruses. Here, our aim is to examine the impact of DDX5 on Sindbis virus (SINV) infection.
Mots clés
DDX17, DDX5, Helicase, RNA, Sindbis virus
Référence
Virol J. 2024 03 29;21(1):76