Increase of OH radical yields due to the decomposition of hydrogen peroxide by gold nanoparticles under X-ray irradiation.
Fiche publication
Date publication
mars 2024
Journal
RSC advances
Auteurs
Membres identifiés du Cancéropôle Est :
Pr FROMM Michel, Pr ROUX Stéphane
Tous les auteurs :
Okazaki Y, Kusumoto T, Roux S, Hirayama R, Fromm M, Bazzi R, Kodaira S, Kataoka J
Lien Pubmed
Résumé
We elucidate the decomposition mechanism of hydrogen peroxide, which is formed by water radiolysis, by gold nanoparticles (GNPs) under X-ray irradiation. The variations in yields of hydrogen peroxide generated in the presence of GNPs are evaluated using the Ghormley technique. The increase of yields of OH radicals has been quantified using Ampliflu® Red solutions. Almost all hydrogen peroxide generated by irradiation of <25 Gy is decomposed by GNPs, while the yield of OH radicals increases by 1.6 times. The amount of OH radicals thus obtained is almost equivalent to that of the decomposed hydrogen peroxide. The decomposition of hydrogen peroxide is an essential reaction to produce additional OH radicals efficiently in the vicinity of GNPs.
Référence
RSC Adv. 2024 03 20;14(14):9509-9513