Anatomy-based correction of kidney PVE on [Formula: see text] SPECT images.

Fiche publication


Date publication

février 2024

Journal

EJNMMI physics

Auteurs

Membres identifiés du Cancéropôle Est :
Pr NAMER Izzie-Jacques, Dr POROT Clémence


Tous les auteurs :
Salvadori J, Allegrini O, Opsommer T, Carullo J, Sarrut D, Porot C, Ritzenthaler F, Meyer P, Namer IJ

Résumé

In peptide receptor radionuclide therapy (PRRT), accurate quantification of kidney activity on post-treatment SPECT images paves the way for patient-specific treatment. Due to the limited spatial resolution of SPECT images, the partial volume effect (PVE) is a significant source of quantitative bias. In this study, we aimed to evaluate the performance and robustness of anatomy-based partial volume correction (PVC) algorithms to recover the accurate activity concentration of realistic kidney geometries on [Formula: see text]Lu SPECT images recorded under clinical conditions.

Mots clés

Lu, Partial volume correction, Partial volume effect, Peptide receptor radionuclide therapy, SPECT imaging

Référence

EJNMMI Phys. 2024 02 6;11(1):15