Accumulation of Carbamylation-Derived Products in Aneurysmal Aorta.
Fiche publication
Date publication
janvier 2024
Journal
Journal of vascular research
Auteurs
Membres identifiés du Cancéropôle Est :
Pr GILLERY Philippe
Tous les auteurs :
Doué M, Marques G, Okwieka A, Gorisse L, Piétrement C, Gillery P, Jaisson S
Lien Pubmed
Résumé
Carbamylation is a nonenzymatic post-translational modification of proteins characterized by the binding of isocyanic acid to amino groups of proteins, which leads to the alteration of their properties. An increase in serum carbamylation-derived products, including homocitrulline (HCit), has been shown to be associated with the development of cardiovascular diseases.
Mots clés
Abdominal aortic aneurysm, Carbamylation, Cardiovascular diseases, Homocitrulline, Nonenzymatic post-translational modifications
Référence
J Vasc Res. 2024 01 19;:1-8