Management of a rare mandibular giant cell tumor of bone by neoadjuvant denosumab therapy and surgery: A 4-year follow-up case report.
Fiche publication
Date publication
octobre 2023
Journal
International journal of surgery case reports
Auteurs
Membres identifiés du Cancéropôle Est :
Pr KURTZ Jean-Emmanuel
Tous les auteurs :
Klienkoff P, Weingertner N, Geyer L, Gros CI, Kurtz JE, Bornert F
Lien Pubmed
Résumé
Giant cell tumor of bone (GCTB) is a very rare tumor encountered in the jaws and its histology is quite similar to the more common giant cell granuloma of the jaws (GCGJ). These two entities can be easily confused in maxillofacial region. They are classically managed surgically, but in some localizations and in specific medical-surgical contexts, neoadjuvant therapy with denosumab may be indicated. This report tends to reinforce existing evidence in favor of the use of a neoadjuvant approach, particularly for localization of GCTB in the orofacial region.
Mots clés
Case report, Denosumab, Giant cell tumor of bone, Mandible, Oral surgery
Référence
Int J Surg Case Rep. 2023 10 30;112:108980