Immune changes in hilar tumor draining lymph nodes following node sparing neoadjuvant chemoradiotherapy of localized cN0 non-small cell lung cancer.
Fiche publication
Date publication
novembre 2023
Journal
Frontiers in oncology
Auteurs
Membres identifiés du Cancéropôle Est :
Dr MARTIN Etienne, Dr PAGES Pierre-Benoit
Tous les auteurs :
Khalifa J, Thébault N, Scarlata CM, Norkowski E, Massabeau C, Brouchet L, Peries Bataille S, Casaroli C, Vaz L, Valle C, Sarot E, Saint-Laurent N, Martin E, Pages PB, Millière A, Mazières J, Cohen-Jonathan Moyal E, Lauzéral-Vizcaïno F, Ayyoub M
Lien Pubmed
Résumé
While much progress has been accomplished in the understanding of radiation-induced immune effects in tumors, little is known regarding the mechanisms involved at the tumor draining lymph node (TDLN) level. The objective of this retrospective study was to assess the immune and biological changes arising in non-involved TDLNs upon node sparing concurrent chemoradiotherapy (CRT) of non-small cell lung cancer (NSCLC) tumors.
Mots clés
immune changes, lymph nodes sparing irradiation, non small cell lung cancer (NSCLC), radiotherapy, tumor draining lymph node (TDLN)
Référence
Front Oncol. 2023 11 22;13:1269166