Computed Tomography Bone Imaging: Pushing the Boundaries in Clinical Practice.
Fiche publication
Date publication
août 2023
Journal
Seminars in musculoskeletal radiology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr GILLET Pierre
Tous les auteurs :
Gillet R, Boubaker F, Hossu G, Thay A, Gillet P, Blum A, Teixeira PAG
Lien Pubmed
Résumé
Bone microarchitecture has several clinical implications over and above estimating bone strength. Computed tomography (CT) analysis mainly uses high-resolution peripheral quantitative CT and micro-CT, research imaging techniques, most often limited to peripheral skeleton assessment. Ultra-high-resolution (UHR) CT and photon-counting detector CT, two commercially available techniques, provide images that can approach the spatial resolution of the trabeculae, bringing bone microarchitecture analysis into clinical practice and improving depiction of bone vascularization, tumor matrix, and cortical and periosteal bone. This review presents bone microarchitecture anatomy, principles of analysis, reference measurements, and an update on the performance and potential clinical applications of these new CT techniques. We also share our clinical experience and technical considerations using an UHR-CT device.
Mots clés
Humans, Tomography, X-Ray Computed, Cancellous Bone, Radiopharmaceuticals
Référence
Semin Musculoskelet Radiol. 2023 08;27(4):397-410