A new triterpene saponin and known compounds from the polar extract of L. and evaluation of their antioxidant activity.
Fiche publication
Date publication
septembre 2023
Journal
Natural product research
Auteurs
Membres identifiés du Cancéropôle Est :
Dr ALABDULMAGID Abdulmagid
Tous les auteurs :
Lakhal H, Kabouche A, Kabouche Z, Bechkri S, AlabdulMagid A, Voutquenne-Nazabadioko L, Harakat D
Lien Pubmed
Résumé
A new triterpene saponin, 2, 3, 21, 23-tetrahydroxyolean-12-en-28-oic-acid-28--β-D- glucosyl-(2''→1')-β-D-glucoside (), was isolated from the -butanol extract of dried aerial parts of L. (Lamiaceae) in addition to two known flavonoids, apigenin 7--β-D-glucoside (), threo-guaiacylglycerol 3--[6---hydroxybenzoyl]-β-D-glucoside (), luteolin 7--β-D-glucoside (), verbascoside () and rosmarinic acid (). The structure elucidation of these compounds was based on analyses of spectroscopic data including 1D-, 2D-NMR and HR-ESI-MS techniques and by comparing their NMR data with those reported in the literature. Compound exhibited the highest antioxidant activity in DPPH assay (IC<3.00 µg/mL) which was better than the standards BHA, BHT, Trolox and ascorbic acid.
Mots clés
Salvia argentea L, antioxidant activity, flavonoids, lamiaceae, polyphenols, rosmarinic acid, triterpene saponin
Référence
Nat Prod Res. 2023 09 25;:1-6