Management of the vertebrae as an organ at risk in paediatric radiotherapy clinical trials: initial QUARTET experience.
Fiche publication
Date publication
juillet 2023
Journal
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Auteurs
Membres identifiés du Cancéropôle Est :
Dr BERNIER-CHASTAGNER Valérie
Tous les auteurs :
Turcas A, Kelly SM, Bernier-Chastagner V, Bolle S, Cameron A, Corning C, Clementel E, Dieckmann K, Davila Fajardo R, Gaze MN, Laprie A, Magelssen H, Meroni S, Pignoli E, Safwat A, Scarzello G, Talbot J, Timmermann B, Boterberg T, Mandeville HC
Lien Pubmed
Résumé
Irradiation of the vertebrae in prepubertal patients, if non-homogenous, can result in future growth deformities including kyphoscoliosis. Vertebral delineation and dosimetry were assessed for 101 paediatric cases reviewed within QUARTET-affiliated trials. Despite the availability of published consensus guidelines, a high variability in vertebral delineation was observed, with impact on dosimetry.
Mots clés
Pediatrics, Quality Assurance, Vertebrae, Quality Control, clinical trial, radiation oncology, radiotherapy
Référence
Radiother Oncol. 2023 07 17;:109810