Parental occupational exposure to solvents and risk of developing testicular germ cell tumors among sons: a French nationwide case-control study (TESTIS study).

Fiche publication


Date publication

septembre 2023

Journal

Scandinavian journal of work, environment & health

Auteurs

Membres identifiés du Cancéropôle Est :
Dr KOSCINSKI Isabelle, Pr FAUQUE Patricia


Tous les auteurs :
Guth M, Lefevre M, Pilorget C, Coste A, Ahmadi S, Danjou A, Dananché B, Praud D, Koscinski I, Papaxanthos A, Blagosklonov O, Fauque P, Pérol O, Schüz J, Bujan L, Olsson A, Fervers B, Charbotel B,

Résumé

The etiology of testicular germ cell tumors (TGCT) is suspected to be related to prenatal environmental risk factors. Some solvents have potential endocrine disrupting or carcinogenic properties and may disrupt male genital development in utero. The aim of this study was to examine the association between parental occupational exposure to solvents and TGCT risk among their offspring.

Mots clés

Infant, Newborn, Female, Pregnancy, Male, Humans, Aged, Testis, Nuclear Family, Solvents, Case-Control Studies, Neoplasms, Germ Cell and Embryonal, epidemiology, Petroleum

Référence

Scand J Work Environ Health. 2023 09 1;49(6):405-418