A comparison of treatment effect sizes in matched phase 2 and phase 3 trials of advanced therapeutics in inflammatory bowel disease: systematic review and meta-analysis.
Fiche publication
Date publication
août 2023
Journal
Clinical and translational gastroenterology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr PEYRIN-BIROULET Laurent
Tous les auteurs :
Hanzel J, Solitano V, Zou L, Zou GY, Peyrin-Biroulet L, Danese S, Singh S, Ma C, Wils P, Jairath V
Lien Pubmed
Résumé
Phase 2 trials are fundamental to the rational and efficient design of phase 3 trials. We aimed to determine the relationship of treatment effect size estimates from phase 2 and phase 3 clinical trials on advanced therapeutics in inflammatory bowel disease.
Référence
Clin Transl Gastroenterol. 2023 08 14;: