Differential formation of stress-granules in radiosensitive and radioresistant HNSCC cells.

Fiche publication


Date publication

août 2023

Journal

International journal of radiation oncology, biology, physics

Auteurs

Membres identifiés du Cancéropôle Est :
Dr TOMASETTO Catherine


Tous les auteurs :
Louati S, Wozny AS, Malesys C, Daguenet E, Ladjohounlou R, Alphonse G, Tomasetto C, Magné N, Lafrasse CR

Résumé

Stress granules (SGs) are cytoplasmic aggregates in which mRNAs and specific proteins are trapped in response to a variety of damaging agents. They participate in the cellular defense mechanisms. Currently, their mechanism of formation in response to ionizing radiation and their role in tumor-cell radiosensitivity remain elusive.

Référence

Int J Radiat Oncol Biol Phys. 2023 08 22;: