Biochemical and functional characteristics of stored (double-dose) buffy-coat platelet concentrates treated with amotosalen and a prototype UVA light-emitting diode illuminator.
Fiche publication
Date publication
août 2023
Journal
Transfusion
Auteurs
Membres identifiés du Cancéropôle Est :
Dr MANGIN Pierre
Tous les auteurs :
Brouard N, Pissenem-Rudwill F, Mouriaux C, Haas D, Galvanin A, Kientz D, Mangin PH, Isola H, Hechler B
Lien Pubmed
Résumé
Pathogen reduction of platelet concentrates (PCs) using amotosalen and broad-spectrum UVA illumination contributes to the safety of platelet transfusion by reducing the risk of transfusion-transmitted infections. We evaluated the in vitro quality of stored buffy-coat (BC) PCs treated with amotosalen and a prototype light-emitting diode (LED) illuminator.
Mots clés
INTERCEPT, amotosalen, platelets, storage lesion, transfusion medicine
Référence
Transfusion. 2023 08 24;: