CroMaSt: a workflow for assessing protein domain classification by cross-mapping of structural instances between domain databases and structural alignment.
Fiche publication
Date publication
juin 2023
Journal
Bioinformatics advances
Auteurs
Membres identifiés du Cancéropôle Est :
Dr DEVIGNES Marie-Dominique
Tous les auteurs :
Dhondge H, Chauvot de Beauchêne I, Devignes MD
Lien Pubmed
Résumé
Protein domains can be viewed as building blocks, essential for understanding structure-function relationships in proteins. However, each domain database classifies protein domains using its own methodology. Thus, in many cases, domain models and boundaries differ from one domain database to the other, raising the question of domain definition and enumeration of true domain instances.
Référence
Bioinform Adv. 2023 06 27;3(1):vbad081