Alteration of innate lymphoid cell homeostasis mainly concerns salivary glands in primary Sjögren's syndrome.
Fiche publication
Date publication
mai 2023
Journal
RMD open
Auteurs
Membres identifiés du Cancéropôle Est :
Dr DUMORTIER Hélène, Pr GOTTENBERG Jacques-Eric
Tous les auteurs :
Kawka L, Felten R, Schleiss C, Fauny JD, Le Van Quyen P, Dumortier H, Monneaux F, Gottenberg JE
Lien Pubmed
Résumé
Innate lymphoid cells (ILCs) are a cell population implicated in the pathogenesis of various chronic inflammatory diseases, but little is known about their role in primary Sjögren's syndrome (pSS). The aim of this study was to assess the frequency of ILC subsets in peripheral blood (PB) and their quantity and location in minor salivary glands (MSGs) in pSS.
Mots clés
Autoimmunity, Sjogren's Syndrome, T-Lymphocyte subsets
Référence
RMD Open. 2023 05;9(2):