Laboratory diagnosis of heparin-induced thrombocytopenia: A retrospective experience.
Fiche publication
Date publication
avril 2023
Journal
Journal of clinical laboratory analysis
Auteurs
Membres identifiés du Cancéropôle Est :
Pr MAUVIEUX Laurent, Dr ROLLAND Delphine
Tous les auteurs :
Herb A, Depierreux M, Wimmer J, Rolland D, Tebacher M, Lambert A, Ladhari C, Cristinar M, Delabranche X, Krummel T, Paya D, Schenck M, Mauvieux L, Sattler L
Lien Pubmed
Résumé
Heparin-induced thrombocytopenia (HIT) is a severe complication of heparin therapy associated with thrombosis that requires a quick diagnosis. Therefore, laboratory assays must provide an accurate and swift answer. This work aims to evaluate the performances of an ELISA assay, especially when combined with 4T risk score, and a functional assay.
Mots clés
adverse effects, heparin, platelet factor 4, thrombocytopenia, thrombosis
Référence
J Clin Lab Anal. 2023 04 23;:e24884