Impact of selective reporting of antibiotic susceptibility testing results for urinary tract infections in the outpatient setting: A prospective controlled before-after intervention study.

Fiche publication


Date publication

mars 2023

Journal

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

Auteurs

Membres identifiés du Cancéropôle Est :
Pr THILLY Nathalie


Tous les auteurs :
Simon M, Fougnot S, De Monchy P, Duda A, Thilly N, Pulcini C,

Résumé

The use of selective reporting of antibiotic susceptibility testing (AST) results is a recommended antimicrobial stewardship strategy to improve the appropriateness of antibiotic prescriptions. We conducted a large, pragmatic, prospective, multicentre, controlled (selective reporting versus complete reporting) before-after intervention study to assess the impact of selective reporting of AST results for Escherichia coli-positive urine cultures on the prescription of broad-spectrum antibiotics carrying a higher risk of selection of resistance (i.e., amoxicillin-clavulanate, third-generation cephalosporins, and quinolones) in the outpatient setting. We also looked for possible unintended clinical consequences of the intervention leading to consultations and/or hospitalisations.

Mots clés

Microbiology, Outpatient setting, Urinary tract infections, antibiotic prescriptions, antimicrobial stewardship

Référence

Clin Microbiol Infect. 2023 03 13;: