Serum carboxymethyllysine concentration is associated with erosive hand osteoarthritis.
Fiche publication
Date publication
mars 2023
Journal
Osteoarthritis and cartilage
Auteurs
Membres identifiés du Cancéropôle Est :
Pr GILLERY Philippe
Tous les auteurs :
Cambon-Binder A, Jaisson S, Tuffet S, Courties A, Eymard F, Okwieka A, Gillery P, Miquel A, Rousseau A, Crema MD, Berenbaum F, Sellam J
Lien Pubmed
Résumé
Carboxymethyllysine (CML) and homocitrulline (HCit) are the products of two non-enzymatic post-translational modifications of protein, a process related to age. We investigated whether serum CML and HCit concentrations were associated with hand osteoarthritis (HOA), especially erosive HOA.
Mots clés
Advanced glycation end-products, Running headline: Serum glycoxydation in hand osteoarthritis, ageing, biomarker, carbamylation, carboxymethyllysine, erosive hand osteoarthritis, glycoxidation, homocitrulline
Référence
Osteoarthritis Cartilage. 2023 03 15;: